新疆地区维、汉中青年脑梗死患者脑血管狭窄分布比较  

A Comparative Study of Distribution of Cerebral Artery Stenosis of Young and Middle-aged Patients with Cerebral Infarction between Uygur and Han Nationality in Xinjiang Area

作　　者：葛晓敏 雷晶[1] 马建华[1] 

机构地区：[1]新疆医科大学第一附属医院神经内科,乌鲁木齐830054

出　　处：《神经损伤与功能重建》2017年第5期403-406,共4页Neural Injury and Functional Reconstruction

基　　金：国家自然科学基金(No.81060097)

摘　　要：目的:比较新疆地区维、汉中青年脑梗死患者的脑血管狭窄相关因素及分布差异性。方法:回顾性选择维吾尔族脑梗死患者36例(维吾尔族组)及汉族脑梗死患者92例(汉族组),经DSA证实有血管狭窄,收集患者的临床资料,并进行比较。结果:与维吾尔族组比较,汉族组前循环血管病变率显著降低,后循环及前-后循环联合病变率升高(P<0.05)。2组均以颅内血管病变多见,与维吾尔族组比较,汉族组颅内血管狭窄或闭塞率明显降低,颅外血管狭窄或闭塞率及颅内-外联合病变率升高(均P<0.05)。与维吾尔族组相比,汉族组颅外血管轻、中度狭窄的比率较低,重度狭窄、闭塞率较高(P<0.05)。与维吾尔族组比较,汉族组椎动脉颅内段、大脑中动脉、大脑后动脉血管病变率升高,大脑前动脉、基底动脉、颈内动脉颅内段病变率降低(P<0.05)。与维吾尔族组比较,汉族组高同型半胱氨酸血症、体质指数≥25 kg/m2、高血压发生率降低(P<0.05),吸烟、饮酒比例升高(P<0.05)。结论:维吾尔族与汉族中青年脑梗死患者脑血管狭窄的分布特点不同,脑动脉粥样硬化危险因素分布有民族差异性。Objective：To Compare distribution and correlative factors of cerebral artery stenosis of young and middle-aged patients with cerebral infarction between Xinjiang Uygur and Han Nationality.Methods：Patients diagnosed with ischemic cerebrovascular disease,confirmed with vascular stenosis by DSA,were enrolled retrospectively,including 36 cases of Uygur Nationality patients （Uygur group） and 92 cases of Han Nationality （Han group）.The clinical data was collected and compared.Results：Compared with Uygur group,the incidence ratio of anterior circulation artery stenosis in Han group was significantly lower,and the incidence ratio of the posterior circulation and anterior-posterior circulation artery stenosis was significantly higher （P〈0.05）.The intracranial vascular lesions were common in both the two groups.Compared with Uygur group,the incidence ratio of intracranial artery stenosis or occlusion in Han group was significantly lower,and the incidence ratio of extracranial and intracranial-extracranial artery stenosis or occlusion was significantly higher （P〈0.05）.Compared with the Uygur group,the incidence ratio of mild to moderate stenosis of the external carotid artery was lower in Hangroup,and the ratio of severe stenosis and occlusion was higher （P〈0.05）.Compared with Uygur group,the incidence ratio of vascular lesions of MCA 、IVA、PCA in Han group was significantly higher,and the ratio of vascular lesions of MCA、IVA、PCA was much lower （P〈0.05）.Compared with Uygur group,the incidence ratio of HHcy,BMI≥25 kg/m2,hypertension were much lower （P〈0.05）,and the percentage of smoking and drinking was much higher （P〈0.05）.Conclusion：In the young and middle-aged patients of Uygur Nationality and Han Nationality with cerebral infarction,the distribution of cerebral artery stenosis is different,and there are ethnic differences in the distribution of correlative factors of cerebral atherosclerosis.

关 键 词：脑梗死 狭窄 维吾尔族 汉族 危险因素 

分 类 号：R741[医药卫生—神经病学与精神病学] R741[医药卫生—临床医学]