MR 3D-VIBE序列多期动态增强扫描在原发性肝细胞癌中的应用  

Application of Enhanced MR Multi-Phase Dynamic Scanning with 3D-VIBE Sequence in Hepatocellular Carcinoma

作　　者：李新文[1] 蔡华崧[2] 杨艳红[2] 李畅[2] 董帜[2] 冯仕庭[2] 罗宴吉[2] 

机构地区：[1]深圳市南山区妇幼保健院放射科,广东深圳518067 [2]中山大学附属第一医院医学影像科,广东广州510080

出　　处：《中山大学学报（医学科学版）》2017年第6期900-908,共9页Journal of Sun Yat-Sen University:Medical Sciences

基　　金：广东省自然科学基金(2014A030310484)

摘　　要：【目的】通过对原发性肝细胞癌(HCC)的MR三维容积插入屏气检查(3D-VIBE)多期动态增强扫描与多层螺旋CT(MSCT)增强扫描的对照研究,探讨MR 3D-VIBE序列动态增强扫描在显示HCC的动态强化特点中的价值。【方法】收集23例在我院行上腹部3.0T MR 3D-VIBE多期动态增强扫描及MSCT双期增强扫描的HCC的患者的临床及影像学资料,对比3D-VIBE序列动态增强扫描及MSCT增强扫描显示肿瘤的强化特点。【结果】23例经手术证实共发现23个HCC,MRI 3DVIBE序列检出全部23个病灶,CT检出21个病灶。MRI 3D-VIBE序列多期动态增强扫描中病灶显示为"快进快退"征象者占78.3%(18/23),MSCT增强扫描具有此征象者占54.5%。直径≤3 cm的肿瘤更易在3D-VIBE序列多期动态增强扫描中观察到明显强化征象(P=0.037)。【结论】MR 3D-VIBE序列肝脏进行多期动态增强扫描,提高了HCC尤其是小HCC诊断的敏感性与准确性。【Objective】To investigate the value of multi-phase dynamic enhanced MR scanning with 3 D-VIBE sequence in HCC by comparing with enhanced multiple slice computer tomography(MSCT)scanning.【Method】23 patients who were pathologically proven of HCC,and underwent both abdominal enhanced 3.0 T MR multi-phase dynamic scanning with 3 D-VIBE sequence and enhanced MSCT scanning were enrolled. The enhancement features of HCC on enhanced MR multi-phase dynamic scanning and enhanced CT scanning were compared.【Results】There were 23 lesions confirmed by pathology. All the 23 lesions were detected by enhanced MR multi-phase dynamic scanning with 3 D-VIBE sequence,and 21 lesions were detected by enhanced MSCT scanning. The enhanced features of"fast enhanced and fast washout"in HCC can be observed more frequently on enhanced MR multi-phase dynamic scanning with 3 D-VIBE sequence than enhanced MSCT scanning(78.3% vs 54.5%). Obvious enhancement feature can be observed more frequently on the enhanced MR multi-phase dynamic scanning when the tumor diameter ≤ 3 cm(P=0.037).【Conclusion】The enhanced MR multi-phase dynamic scanning with 3 D-VIBE sequence can greatly improve the sensitivity and accuracy of HCC diagnosis,especially for the small HCC(tumor diameter ≤ 3 cm).

关 键 词：原发性肝细胞癌 磁共振成像 X线断层摄影术 三维容积插入屏气检查 

分 类 号：R73[医药卫生—肿瘤]