部分脾动脉栓塞术对脾静脉及门静脉压力的影响  

The effect of partial splenic embolization on the hemodynamics of splenic and portal venous pressure

作　　者：王军[1] 施东华[1] 华静[2] 沈加林[1] 

机构地区：[1]上海交通大学医学院附属仁济医院肿瘤介入科,200127 [2]上海交通大学医学院附属仁济医院消化科,200127

出　　处：《介入放射学杂志》2017年第11期1022-1024,共3页Journal of Interventional Radiology

基　　金：中国肝炎防治基金会王宝恩肝纤维化研究基金(CFHPC20151013)

摘　　要：目的探讨部分脾动脉栓塞术(PSE)前后脾静脉、门静脉压力变化及其影响因素。方法对14例门静脉高压伴脾功能亢进患者行PSE术治疗,手术前后均采用直接测压法检测脾静脉及门静脉压力,并对比压力变化。术后1~2个月行增强CT复查。结果 PSE术后脾静脉压力较术前明显下降,7例门静脉压力下降明显(>2 cm H2O)。术后复查增强CT显示多数患者食管胃底静脉曲张程度有不同程度改善。结论 PSE术可有效降低脾静脉压力,在降低近期门静脉压力方面影响因素较多。Objective To investigate the changes of splenic and portal venous pressure after partial splenic embolization （PSE）, and to discuss its influence factors. Methods PSE was carried out in 14 patients with portal hypertension complicated by hypersplenism. Before and after PSE, the splenic and portal vein pressure was determined by direct manometry method. The post-operative venous pressure was compared with pre-operative one. Contrast-enhanced CT scan was performed 1-2 months after the treatment. Results After PSE, the splenic venous pressure was decreased obviously, a reduction of more than 2 cmH20 in portal venous pressure was observed in 7 patients. Post- operative reexamination with contrast-enhanced CT scan showed that varying degrees of improvement of esophageal and gastric variees could be observed in most patients. Conclusion PSE can effectively decrease the splenic venous pressure, and there are a lot of factors that may influence the short-term reduction in portal vein pressure.

关 键 词：部分脾动脉栓塞术 脾功能亢进 门静脉高压 

分 类 号：R575.2[医药卫生—消化系统]