莫沙比利与铝碳酸镁咀嚼片联合治疗功能性消化不良的疗效观察及其对不良情绪的影响  

Observation on efficacy of mosapride combined with aluminum magnesium carbonate chewable tablets in the treatment of functional dyspepsia and its effect on adverse emotions

作　　者：蒋丰娟 王文斌[1] 

机构地区：[1]扬州市江都人民医院消化内科,225200

出　　处：《中国实用医药》2017年第30期118-119,共2页China Practical Medicine

摘　　要：目的分析莫沙比利与铝碳酸镁咀嚼片联合治疗功能性消化不良的临床疗效以及对患者不良情绪的影响。方法 100例功能性消化不良患者,随机分为观察组与对照组,每组50例。对照组采用单药铝碳酸镁咀嚼片治疗,观察组在对照组基础上加入莫沙比利治疗,观察比较两组患者的临床治疗效果及治疗前后焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分。结果观察组与对照组的总有效率分别为94.0%和78.0%,观察组总有效率显著优于对照组,差异具有统计学意义(P<0.05)。治疗后,两组患者的SAS评分及SDS评分均低于治疗前,且观察组优于对照组,差异具有统计学意义(P<0.05)。结论莫沙比利联合铝碳酸镁咀嚼片治疗功能性消化不良具有较好的临床疗效,能够显著缓解临床症状,消除焦虑、抑郁情绪,有助于提高患者的生活质量,值得在临床治疗中推广使用。Objective To analyze the clinical efficacy of mosapride combined with aluminum magnesium carbonate chewable tablets in the treatment of functional dyspepsia and its effect on adverse emotions. Methods A total of 100 functional dyspepsia patients were randomly divided into observation group and control group, with 50 cases in each group. The control group was treated with aluminum magnesium carbonate chewable tablets, and the observation group was also treated with mosapride on the basis of the control group. Observation and comparison were made on clinical treatment effect, self-rating anxiety scale （SAS） score and self-rating depression scale （SDS） score before and after treatment between two groups. Results The observation group and control group had total effective rate respectively as 94.0% and 78.0%, and the observation group had obviously better total effective rate than the control group. Their difference was statistically significant （/~〈0.05）. After treatment, both groups had lower SAS and SDS score than before treatment, an the observation group was better than the control group. Their difference was statistically significant （/9〈0.05）. Conclusion Combination of mosapride and aluminum magnesium carbonate chewable tablets shows excellent clinical efficacy in treating functional dyspepsia and its effect on adverse emotions, and it can significantly alleviate the clinical symptoms and eliminate anxiety and depression. It is also helpful to improve the quality of life of patients. It is worth popularizing and using in clinical treatment.

关 键 词：莫沙比利 铝碳酸镁咀嚼片 功能性消化不良 不良情绪 

分 类 号：R57[医药卫生—消化系统]