注射用血塞通对不同中医证型短暂性脑缺血患者微栓子信号的影响  

Influence of Xuesaitong Injection on The Different TCM Syndromes of Microembolic Signal of Patients with TIA

作　　者：史敏[1] 杨东东[1] 罗丹青[2] 肖文 王倩男[2] 宁金丽 

机构地区：[1]成都中医药大学附属医院神经内科,成都610000 [2]成都中医药大学,成都610000

出　　处：《中国中医基础医学杂志》2017年第10期1413-1416,1426,共5页JOURNAL OF BASIC CHINESE MEDICINE

基　　金：基金项目:国家中医药管理局(JDZX2012133)-糖尿病合并缺血性卒中急性期中西结合规范化治疗方案的临床评价研究

摘　　要：目的:探讨注射用血塞通对MCA粥样硬化性血管狭窄伴MES阳性TIA患者MES数量的影响。方法:选取98例住院患者随机分成常规治疗组和注射用血塞通组,常规治疗组给予TIA常规二级预防治疗,注射用血塞通组在常规治疗的基础上给予注射用血塞通治疗15 d,比较2组患者治疗前后MES数量及不同中医证型患者治疗前后MES数量,并在第3、6个月随访缺血事件发生率。结果:通过TCD对MES监测,2组MES的数量都明显减少,注射用血塞通组MES数量减少更明显,注射用血塞通组阴虚风动型、风痰入络型患者治疗前后MSE差值明显高于常规治疗组,并在随访中发现,注射用血塞通组缺血性事件发生率明显减少。结论:注射用血塞通增加了常规二级预防,减少MCA粥样硬化性血管狭窄伴MES阳性TIA患者MES数量和缺血性事件发生率。常规二级预防减少阴虚风动型患者MES数量最为明显,注射用血塞通最为明显地增加了常规二级预防减少风痰入络型患者MES数量的作用。Objective： To explore the xuesaitong injection for MCA atherosclerotic vascular stenosis with MES, the influence of the number of MES in TIA patients. Method： Select 98 cases of hospitalized patients, randomly divided into conventional treatment group and the injection group, routine treatment group was given TIA conventional secondary prevention treatment, injection group was given Xuesaitong injection treatment on the basis of convention treatment for 15 days. Compares two groups of patients before and after treatment of MES, and different type of syndrome before and after treatment in patients with number of MES, and ischemic events nate in 3, 6 months follow-up. Result： Through TCD monitoring of MES, both groups decreased significantly, the number of MES of injection group of MES decreased more significantly, injection group of Yin deficiency type pneumatic type, wind phlegm into complex before and after treatment in patients with MSE difference significantly higher than the conventional treatment group, and during follow-up found that injection group significantly reduce the incidence of ischemic events. Conclusion： Xuesaitong Injection increased blood routine secondary prevention to reduce the MCA atherosclerotic vascular stenosis with MES positive patients with TIA MES number and incidence of ischemic events. Conventional secondary prevention to reduce the number of patients with Yin deficiency type pneumatic MES is the most obvious, the Xuesaitong injection increased blood routine secondary prevention to reduce the patients with wind Dhle~,m into the complex number of MES most obviacslv.

关 键 词：短暂性脑缺血发作 微栓子 大脑中动脉狭窄 注射用血塞通 中医证型 

分 类 号：R743.31[医药卫生—神经病学与精神病学]