质子泵抑制剂临床应用新领域  

New Fields of Clinical Application of Proton Pump Inhibitor

作　　者：尚琪[1] 郭丽芳[1] 张翠霞[1] 温萌[1] 李赟 尹跃霏 陈亚丽 张德奎[1] 

机构地区：[1]兰州大学第二医院消化科,730030

出　　处：《胃肠病学》2017年第11期696-699,共4页Chinese Journal of Gastroenterology

基　　金：国家自然科学基金项目(81470808)

摘　　要：质子泵抑制剂(PPI)是治疗胃酸异常分泌和酸相关性疾病的一线药物,对消化性溃疡、幽门螺杆菌(Hp)感染、上消化道出血、胃食管反流病(GERD)等疾病疗效显著。近期研究表明PPI可应用于其他临床领域,如肿瘤、肺纤维化、房颤、结核菌感染、早产等,为这些疾病的治疗提供了新思路。本文就PPI的临床应用新领域作一综述。Proton pump inhibitor （PPI） is the firstline drug for treatment of abnormal secretion of gastric acid and acid related diseases, and is effective in the treatment of peptic ulcer, Helicobacter pylori （Hp） infection, upper gastrointestinal bleeding and gastroesophageal reflux disease （GERD）. Recent studies have shown that PPI could be used in other clinical fields, such as tumor, pulmonary fibrosis, atrial fibrillation, tuberculosis infection and premature delivery, which provides new insights for the treatment of these diseases. This article reviewed the new fields of clinical application of PPI.

关 键 词：质子泵抑制剂 肿瘤 肺纤维化 心房颤动 早产 治疗 

分 类 号：R57[医药卫生—消化系统]