63例湿疹样唇炎患者斑贴试验临床分析  

Clinical analysis of patch test in 63 patients with eczematous cheilitis

作　　者：杨素莲[1] 尹颂超[1] 张香香[1] 陈海燕[1] 张云青[1] 赖维[1] 

机构地区：[1]中山大学附属第三医院皮肤性病科,广东广州510630

出　　处：《中国卫生检验杂志》2017年第21期3118-3120,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的了解湿疹样唇炎患者接触性变应原的分布及其特点。方法对2014年11月-2017年4月湿疹样唇炎患者,采用日常生活系列斑贴试剂盒检测患者的接触变应原。结果 63例检测患者中,56例检出1种或1种以上变应原,阳性率为88.89%。阳性率高的前6位变应原为氯化镍(23.81%)、芳香族混合物(20.63%)、十二醇硫酸钠(19.05%)、氯化钴(17.46%)、硫酸镍(15.87%)和香料混合物(14.29%);不同年龄、不同性别患者斑贴试验结果之间差异均无统计学意义(P>0.05)。结论湿疹样唇炎患者常见的变应原为氯化镍、芳香族混合物、十二醇硫酸钠、氯化钴、硫酸镍和香料混合物。Objective To investigate the distribution and characteristics of common allergens in the patients with eczematous cheilitis. Methods The patients with eczematous cheilitis from November 2014 to April 2017 were collected and tested by the patch test kit of daily life series. Results 63 cases with eczematous cheilitis were collected. More than one allergens were detected in 56 cases（ 88. 89%）. The top 6 allergens were nickel chloride（ 23. 81%）,aromatic compounds（ 20. 63%）,sodium dodecyl sulfate（ 19. 05%）,cobalt chloride（ 17. 46%）,nickel sulfate（ 15. 87%） and spice mixture（ 14. 29%）. There was no statistical significance on the differences of patch test results between different genders and among age groups（ P 〉0. 05）. Conclusion Nickel chloride,aromatic compounds,sodium dodecyl sulfate,cobalt chloride,nickel sulfate and spice mixture are common allergens in patients with eczematous cheilitis.

关 键 词：湿疹样唇炎 斑贴试验 变应原 

分 类 号：R781.56[医药卫生—口腔医学]