Critical role of immunogenic cell death in cancer therapy  

作　　者：tian xia 

机构地区：[1]division of nanomedicine,department of medicine,university of california los angeles,CA 90095,USA [2]center for environmental implications of nanotechnology(cein),california nano systems institute(cnsi),university of california,CA 90095,USA [3]state key laboratory of environmental chemistry and ecotoxicology,research center for eco-environmental sciences,chinese academy of sciences,Bejing 100085,China

出　　处：《Science Bulletin》2017年第21期1427-1429,共3页科学通报（英文版）

摘　　要：In traditional cancer therapy, including chemo and radiation therapy, the goal is always to kill as much cancer cells as possible. However, the truth is that it is difficult to kill 100% of the cancer cells for these therapies and the remaining cells often leads to relapse. So the million-dollar question is, how to eliminate the majority of the remaining cancer cells so that the disease can be manageable in a clinical setting. Currently the best approach that is attracting much attention is cancer immune therapy and excit- ing developments in this field have led to cure in some cases that is unimaginable before [1]. There are two major parts to cancer immune therapy that need to work together to make the therapy successful. One is on the reversal of immune suppressive microen- vironment in cancer to allow the immune cells to target the tumor.In traditional cancer therapy,including chemo and radiation therapy,the goal is always to kill as much cancer cells as possible.However,the truth is that it is difficult to kill 100%of the cancer cells for these therapies and the remaining cells often leads to relapse.So the million-dollar question is,how to eliminate the majority of the remaining cancer cells so that the disease can be manageable in a clinical setting.Currently the best approach that is attracting much attention is cancer immune therapy and exciting developments in this field have led to cure in some cases

关 键 词：Critical role of immunogenic cell death cancer therapy 

分 类 号：R730.5[医药卫生—肿瘤]