肝脏损伤新的血清学标志物的研究进展  

New serological markers for liver damage

作　　者：宋华峰[1] 胥萍[1,2] 

机构地区：[1]苏州市第五人民医院检验中心,江苏省苏州市215007 [2]苏州市第五人民医院结核病防治重点实验室,江苏省苏州市215007

出　　处：《世界华人消化杂志》2017年第30期2681-2688,共8页World Chinese Journal of Digestology

基　　金：江苏省自然科学基金资助项目;No.BK20161230;江苏省卫生计生委基金资助项目;No.H201652;苏州市科技局应用基础研究计划基金资助项目;No.SYS201433~~

摘　　要：肝脏是人体内最为重要的解毒器官,当其损伤后会严重影响人体的健康状况.目前临床上普遍用来诊断肝损伤的血清标志物为谷丙转氨酶(alanine transaminase,ALT)和谷草转氨酶(aspartate transaminase,AST),由于其他疾病也能够导致其含量增加,所以其降低了其临床诊断价值.为了更精确的诊断肝损伤,我们需要寻找新的潜在血清标志物来完善ALT、AST所提供的信息,从而使患者能够得到及时的治疗.The liver is the most important detoxification organ in the human body, and the damage to the liver will seriously affect the health of the body. Alanine transaminase（ALT） and aspartate transaminase（AST） are the most widely used clinical biochemical markers for liver injury. However, elevated serum ALT and AST levels can also occur in other diseases, which reduces their diagnostic value in liver injury. In order to diagnose liver damage more accurately, we need to find serum markers for liver injury.

关 键 词：肝损伤 谷丙转氨酶 谷草转氨酶 血清学 

分 类 号：R575[医药卫生—消化系统]