纤维素酶的糖基化  

Progress in cellulase glycosylation

作　　者：马亚楠 王明钰[1] 徐海[1] 

机构地区：[1]山东大学微生物技术国家重点实验室,山东济南250100

出　　处：《微生物学报》2017年第12期1761-1768,共8页Acta Microbiologica Sinica

基　　金：国家科技支撑计划(2014BAD02B07);山东省重点研发计划(2016GSF121040)~~

摘　　要：木质纤维素价格低廉,供应充足,且未得到充分开发利用。把纤维素降解成葡萄糖,进而生产纤维素乙醇的技术已经进入商业应用阶段。提高纤维素酶的活性,有利于充分利用自然界中大量存在的木质纤维素,开发生物质资源,以缓解能源危机。糖基化修饰对纤维素酶的活性、稳定性以及其他性质有着重要的影响。因此,对纤维素酶糖基化的了解,以及合理地改善糖基化修饰,可以极大地提高木质纤维素降解速率,有利于工业上液体燃料的生产。Lignocellulose is a cheap, abundant and underutilized bioresource. Cellulases can break down cellulose into glucose that could further be fermented to bioethanol, thus has commercial potentials. The improvement of cellulase production helps the use of the abundantly available lignocellulose, benefits the further exploration of the potential of bioenergy, and assists the relief of the energy crisis. However, glycosylation has an important influence on catalytic activity, thermal stability and other properties. Therefore, the detailed knowledge on cellulase glycosylation is required. Reasonably maniputing cellulase glycosylation modifications can accelerate the hydrolysis of lignocellulose, and contribute to produce liquid biofuels.

关 键 词：木质纤维素 纤维素酶 糖基化 

分 类 号：Q55[生物学—生物化学]