中国大陆医学生近十年自杀意念发生率的Meta分析  

Incidence of suicidal ideation of medical students in China's Mainland over the past ten years: a meta-analysis

作　　者：沈可 黄笛 刘晴[3,4] 任学群 靳英辉 郭毅 曾宪涛[2,3,5] 

机构地区：[1]武汉大学医学部科研与学科建设办公室,武汉430071 [2]武汉大学中南医院循证与转化医学中心/武汉大学第二临床学院循证医学与临床流行病学教研室,武汉430071 [3]武汉大学循证与转化医学中心,武汉430071 [4]武汉大学健康学院预防医学系,武汉430071 [5]河南大学循证医学中心/河南大学淮河医院循证医学中心,河南开封475000 [6]天津中医药大学护理学院/天津中医药大学循证护理中心,天津300193

出　　处：《中国循证医学杂志》2017年第11期1332-1339,共8页Chinese Journal of Evidence-based Medicine

基　　金：国家自然科学基金青年项目(编号:81603496);中华医学会医学教育分会和中国高等教育学会医学教育专业委员会2016年医学教育研究立项课题(编号:2016B-PG034);2017年度武汉大学医学部教学研究项目立项课题(编号:2017031)

摘　　要：目的采用Meta分析探讨近十年中国大陆医学生自杀意念发生率,为预防医学生自杀及开展医学生心理健康教育提供参考依据。方法计算机检索Pub Med、CNKI、Wan Fang Data和CBM数据库,搜集2007年1月1日至2017年5月31日发表的有关中国大陆医学生自杀意念的文献,由两名研究者独立进行文献筛选、资料提取和评价纳入研究的偏倚风险后,采用Stata 12.0软件进行Meta分析。采用亚组分析和Meta回归分析探索异质性来源,并通过敏感性分析探索单个研究对合并效应量的影响。结果共纳入30篇文献,包括58 757名中国大陆医学生,自杀意念发生率介于0.84%~41.35%。纳入研究间的异质性较大(I2=99.1%,P<0.001),基于随机效应模型的中国大陆医学生的合并自杀意念发生率为12.51%[95%CI(9.72%,15.60%)]。单个协变量和多个协变量的Meta回归分析发现异质性仅与调查工具不同有关(P<0.01),而未发现与其他研究因素相关(P>0.1)。结论中国大陆医学生的自杀意念发生率相对较高,提示应当对此予以重视并制定相关的措施来预防医学生自杀及开展医学生心理健康教育。Objective To estimate the incidence of suicidal ideation of Chinese medical students in China's Mainland over the past ten years by meta-analysis, so as to provide references for suicide prevention and mental health education in Chinese medical students. Methods PubMed, CNKI, WanFang Data and CBM databases were searched for studies investigating the prevalence of suicidal ideation among Chinese medical students in China's Mainland from January ist, 2007 to 31st May, 2017. After study selection according to inclusion and exclusion criterion, data extraction and quality assessment, meta-analysis was conducted using Stata 12.0 software. Heterogeneity was evaluated by performing subgroup analyses and meta-regression. We also used sensitivity analysis to determine the influence of individual studies on the overall prevalence estimates. Results A total of 30 studies with 58 757 participants were included, the individual-study incidence of suicidal ideation ranged from 0.84% to 41.35%, with significant between-study heterogeneity detected （12=99.1%, P〈0.001）, and the pooled incidence by random-effects model was 12.51% with 95%CI 9.72% to 15.60%. Univariate and multivariate meta-regression revealed that instruments were related to heterogeneity （P〈0.01）, but other study-level covariates did not contribute to heterogeneity （P〉0.1）. Conclusion The incidence of suicidal ideation among medical students in China's Mainland is relatively high, calling more attention to this concern and actions in response for suicide prevention and mental health education in Chinese medical students.

关 键 词：中国 医学生 自杀意念 心理健康 META分析 

分 类 号：G444[哲学宗教—心理学] R-4[哲学宗教—发展与教育心理学]