金属有机骨架材料修饰玻碳电极循环伏安法测定维生素C片中抗坏血酸  

Determination of Ascorbic Acid in Vitamin C Tablet by Cyclic Voltammetry at Glassy Carbon Electrode Modified with Metal Organic Framework

作　　者：李庆伟[1,2] 刘峥[1,2] 李海莹[1,2] 郭征楠 魏席 唐群[1,2] 张淑芬[1,2] 

机构地区：[1]桂林理工大学广西电磁化学功能物质重点实验室,桂林541004 [2]桂林理工大学化学与生物工程学院,桂林541004

出　　处：《理化检验（化学分册）》2017年第11期1259-1264,共6页Physical Testing and Chemical Analysis(Part B:Chemical Analysis)

基　　金："广西特聘专家"专项(N02401007012);国家自然科学基金(21266006);广西自然科学基金(2016GXNSFAA380109)

摘　　要：合成了金属有机骨架材料(Zn-MOFs),通过电沉积方法将Zn-MOFs修饰到玻碳电极表面,制得Zn-MOFs修饰玻碳电极。采用循环伏安法在pH 5的磷酸盐缓冲溶液中以扫描速率100mV·s^(-1)对Zn-MOFs修饰玻碳电极进行表征。结果表明:相比于裸玻碳电极,Zn-MOFs修饰玻碳电极提高了抗坏血酸氧化活性。抗坏血酸的线性范围为4×10^(-5)~1×10^(-2) mol·L^(-1),方法的检出限(3s/k)为6.7×10^(-6) mol·L^(-1)。方法用于维生素C片样品的分析,加标回收率为91.0%~109%,测定值的相对标准偏差(n=5)为0.80%~1.9%。The metal organic framework（Zn-MOFs）was synthesized.Zn-MOFs was successfully modified to the glassy carbon electrode surface by electrodeposition method,and then the glassy carbon electrode modified with Zn-MOFs was prepared.The modified electrode was characterized by cyclic voltammetry in phosphate buffer solution of pH 5 at scanning rate of 100 mV·s^（-1）.It was found that the modified electrode could improve the oxidation activity of ascorbic acid compared with bare glassy carbon electrode.Linearity range of ascorbic acid was found between 4×10^（-5） mol·L^（-1） and 1×10^（-2） mol·L^（-1） with detection limit（3 s/k）of 6.7×10^（-6） mol·L^（-1）.The proposed method was applied to the analysis of samples of vitamin C tablet,giving values of recovery and RSD′s（n=5）in the ranges of 91.0%-109% and 0.80%-1.9% respectively.

关 键 词：循环伏安法 金属有机骨架材料 修饰电极 抗坏血酸 维生素C片 

分 类 号：O657.1[理学—分析化学]