头颈部淋巴管研究方法及进展  

Methods and advances in the research of lymphatics in the head and neck

作　　者：郭瑞[1] 田俊[1] 贾越[1] 何鹏飞[1] 靳荣秀 郭珏[1] 王斌全[1] 

机构地区：[1]山西医科大学第一医院耳鼻咽喉头颈外科耳鼻咽喉头颈肿瘤山西省重点实验室山西医科大学耳鼻咽喉研究所,太原030001

出　　处：《中华耳鼻咽喉头颈外科杂志》2017年第11期876-880,共5页Chinese Journal of Otorhinolaryngology Head and Neck Surgery

基　　金：山西省重点研发计划（指南）项目（201603D121039）;山西医科大学第一医院2015年度院基金（YJ1501）

摘　　要：鳞状上皮癌是头颈部最常见的恶性肿瘤。在原发灶已经控制的情况下，是否出现颈部淋巴转移是影响头颈癌预后的重要因素。因此，深入认识头颈部淋巴管的结构和肿瘤经淋巴管转移的机制对于头颈部鳞癌的治疗至关重要，本文综述了文献中有关淋巴管的研究方法，以期能对淋巴管的进一步研究有所启发。The lymphatic system plays an important role in human health and disease. In addition to a role in the immune response, the lymphatics can also serve as a pathway for cancer metastasis. Head and neck squamous cell carcinoma （HNSCC） is one of the most common cancers. In the case where the primary focus has been controlled, cervical lymph node metastasis is one of the most important factors affecting the prognosis of head and neck cancer. Thus, understanding the anatomy of the lymphatic system is of paramount importance in predicting cancer metastasis and to perform proper lymph node dissection in cancer patients. The objective of this review is to summarize current imaging approaches that facilitate both basic science and clinical investigations of lymphatic vasculature. Mutation analysis of the laryngeal lymphatic system may provide a theoretical basis for the diagnosis and treatment of HNSCC.

关 键 词：淋巴管 流动注射分析 免疫组织化学 酶组织化学 染色和标记 

分 类 号：R739.91[医药卫生—肿瘤]