自发性球结膜下出血患者体内血液组分的异常变化特点  

Characteristics of abnormal changes of blood components in the patients with spontaneous subconjunctival hemorrhage

作　　者：段惠义 崔卉 DUAN Huiyi CUI Hui(Department of Ophthalmology, Beijing Changping District Hospital, Beijing 102200, China)

机构地区：[1]北京市昌平区医院眼科,北京102200

出　　处：《中国现代医生》2017年第32期55-58,共4页China Modern Doctor

摘　　要：目的了解自发性球结膜下出血患者体内各血液组分的变化情况,为探讨其发病机制和防治提供参考。方法采用回顾性序列病例研究方法,纳入临床确诊为自发性球结膜下出血患者(患者组)120例及正常人对照组(正常组)120例,按盲法由专业技术人员完成血液样本的常规检查。观察并比较两组血常规的各项参数,进行统计学分析。结果在自发性球结膜下出血患者体内,参数WBC、MPV、MONO%、MONO和BASO较正常组明显升高。而RBC、HGB、HCT、LYM%、PLT、PCT、PDW和P-LCR较正常组明显降低。余下参数与正常组相比,差异无统计学意义。结论自发性球结膜下出血患者体内血液各组分含量或浓度的异常变化提示其可能具有的发病机制与血液成分动态变化有关,或血液成分的异常变化可能导致患者球结膜下出血。此发现将会指导临床对自发性球结膜下出血的认识,有助于临床对自发性球结膜下出血的防治。Objective To understand the changes of blood components in the patients with spontaneous subconjunctival hemorrhage, and to provide a reference for exploring the pathogenesis and prevention and treatment. Methods Retrospective sequence case study was used. 120 patients with spontaneous subconjunctival hemorrhage who were clinical diagnosed were selected as patient group, and 120 healthy subjects were selected in the normal group. The routine examination of blood samples was completed by professional and technical personnel via blind method. The parameters of the routine blood test of the two groups were observed and compared, and the statistical analysis was carried out. Results The parameters of WBC, MPV, MONO%, MONO and BASO in the patients with spontaneous subconjunctival hemorrhage were significantly higher than those in the normal group. RBC, HGB, HCT, LYM%, PLT, PCT, PDW and P-LCR were significantly lower than those in the normal group. The remaining parameters were compared with the normal group, and the differences were not statistically significant. Conclusion The abnormal changes in the content or concentration of blood components in the patients with spontaneous subconjunctival hemorrhage suggest that the potential pathogenesis is related with the dynamic changes of blood components, or the abnormal changes in blood components may lead to bleeding under the conjunctiva. This finding will guide the clinical understanding of spontaneous subconjunctival hemorrhage, which contributes to the clinical prevention and treatment of spontaneous subconjunctival hemorrhage.

关 键 词：自发性球结膜下出血 红细胞 白细胞 血小板 百分比 绝对值 血常规检测 

分 类 号：R777.3[医药卫生—眼科]