不同宫颈组织中4种病原微生物的检测及其相互关系的探讨  

Detection of 4 kinds of pathogenic microbes in cervical tissue and study on the relationship among them

作　　者：李秀荣[1] 陈黎明[1] 

机构地区：[1]中国人民解放军第二一一医院优生优育中心,黑龙江哈尔滨150080

出　　处：《哈尔滨医科大学学报》2002年第4期285-286,共2页Journal of Harbin Medical University

基　　金：哈尔滨市科委资助课题 ( 0 0 6 12 180 2 9)

摘　　要：目的　检测宫颈癌、癌前病变组织、慢性宫颈炎和正常宫颈组织中的人乳头瘤病毒 (HPV)、单纯疱疹病毒Ⅱ型 (HSV 2 )、沙眼衣原体 (CT)和淋球菌 (NG) 4种病原微生物存在状况 ,并分析了其间的关系。方法　采用聚合酶链PCR法。结果　当HPV、HSV 2、CT和NG在宫颈组织中合并感染时 ,由于其间的相互作用 ,可促进宫颈疾病的进程 ,导致宫颈癌的发生。结论　在检测宫颈炎等良性病变发现有病原微生物合并感染时 ,应提高警惕 ,及早用药 。Objective To detect the infection situation of 4 kinds of pathogenic microbes(HPV,HSV-2,CT and NG) in cervical tissue of different diseases.Methods PCR procedure was employed using specific primers for each microbes.Results The combined infection by more than one microbe strengthened the process of the disease and would lead to the pathogenesis of cervical cancer.Conclusion More attention should be payed to the patients who suffered from more than one kind of pathogenic microbe infection in cervical tissue.

关 键 词：子宫颈 病原微生物 宫颈癌 PCR法 

分 类 号：R737.33[医药卫生—肿瘤]