郁南县城乡居民糖尿病视网膜病变流行病学调查  

Epidemiological survey of diabetic retinopathy in urban and rural residents in Yu'nan city

作　　者：钟彩玲 

机构地区：[1]广东省郁南县中医院眼科,广东郁南527100

出　　处：《中国医药科学》2017年第21期44-47,84,共5页China Medicine And Pharmacy

基　　金：广东省云浮市医学科学技术研究基金项目(2015B95)

摘　　要：目的探讨郁南县城乡居民糖尿病视网膜病变的患病率及危险因素,为针对性的治疗及预防来提供科学性依据。方法自2012年3月1日～2015年7月13日,拟选择广东省云浮市郁南县城乡居民为调查对象,收集共计7234例糖尿病(DM)患者参加本次研究,以出现糖尿病视网膜病变(DR)为事件结局,其中DR组患者1593例,非DR组患者5641例,制定调查问卷,收集所有患者的基本资料和实验室敏感指标,运用SPSS17.0对数据处理,以出现DR为因变量,以单因素分析有差异的指标为自变量,行Logistic多因素分析,探讨糖尿病视网膜病变的危险因素。结果此次共计7234例糖尿病患者,其中糖尿病视网膜病变1593例,患病率占22.02%,非增殖期病变1162例(72.94%),增殖期病变431例(27.06%),具有统计学差异(P<0.05);DR组与非DR组患者在平均年龄、平均病程、平均BMI、血压、伴随疾病、吸烟及饮酒史上,有统计学差异(P<0.05);DR组与非DR组患者在血糖(FPG、2hPP、HbAlC)、(尿素氮、肌酐)、(TC、TG、HDL-C、LDL-C)上,有统计学差异(P<0.05);Logistic多因素分析,得出6个与DR发生发展密切相关的因素,年龄、病程、收缩压、血糖(FPG、2hPP、HbAlC)。结论郁南县城乡居民糖尿病视网膜病变的患病率较高,随着年龄增大、糖尿病病程延长、血压升高、血糖(FPG、2hPP、HbAlC)指标升高,糖尿病患者出现DR的危险性增大。Objective To investigate the prevalence and risk factors of diabetic retinopathy in urban and rural areas of Yu＇nan city, and to provide scientific evidence for targeted treatment and Prevention. Methods Urban and rural residents in Yunan city of Cuangdong Province were selected as the research object Since March l ,2012 to July 13,2015, a total of 7234 patients with diabetes mellims （diabetes, mellitus, DM） were enrolled in this study. Diabetic retinopathy was made as a consequence of the event. Among them, there were 1593 patients in group DR , there were 5641 patients in non DR group, and a questionnaire was made to collect the basic data and laboratory sensitive index of all patients.SPSS17.0 was used to handle the Data, DR was taken as dependent variable,index of difference by single factor analysism was taken as independent variables. Logistic muhivariate analysis was conducted to investigate the risk factors of diabetic retinopathy. Results A total of 7234 patients with diabetes were included, among them, the prevalence rate of 1593 cases of diabetic retinopathy was 22.02%, lhe non proliferative lesions were 1162 cases （72.94%）, proliferative lesions were 431 cases （27.06%）, the difference was statistically significant （P 〈 0.05）. the differences of average age, average duration, average BMI, blood pressure, concomitant disease, smoking and drinking history of patients in the DR group and non DR group were statistically significant （P 〈 0.05）; the dift-renees of blood glucose （FPG, 2hPP, HbA1C）, （urea nitrogen, creatinine）, （TC, TG, HDL-C, LDL-C） of patients in the DR group and non DR group were statistically significant （P 〈 0.05）; 6 factors（age, duration of disease, systolic blood pressure, and blood glucose（（FPG, 2hPP, HbA1C） were related to the development of DR by Logistic multivariate analysis. Conelusion The prevalence of diabetic retinopathy is higher in urban and rural areas of yu＇ nan. With the increase of age, the duration of diabetes is prol

关 键 词：郁南县 城乡居民 糖尿病视网膜病变 患病率 危险因素 

分 类 号：R774.1[医药卫生—眼科]