GPC-LC-MS/MS法测定大米中8种农药残留  

Determination of eight pesticide residues in rice by gel permeation chromatography(GPC) combined with liquid chromatography-tandem mass(LC-MS/MS)

作　　者：刘萤[1] 高峰[1] 范斐[1] 刘来福[1] 金晓静 陈向斌 齐娜 皮娜 

机构地区：[1]北京出入境检验检疫局检验检疫技术中心,北京100026 [2]上海屹尧仪器科技发展有限公司,上海201108

出　　处：《分析仪器》2017年第6期161-163,共3页Analytical Instrumentation

基　　金：北京市科技计划课题<国产分析仪器验证与综合评价市场化推广研究与实践>(Z161100003016006)资助

摘　　要：建立了凝胶渗透色谱(GPC)-液相色谱串联质谱(LC-MS/MS)法测定大米中8种农药残留的分析方法。样品用乙腈超声提取,提取液经过凝胶渗透色谱除去大分子杂质后,供LC-MS/MS分析;添加浓度为0.2μg时,回收率为71.3%~111.1%,相对标准偏差为3.64%~12.76%,方法具有自动化程度高、净化效果好、精密度好,分析快速等优点,适用于大米中多农药残留的日常检测工作。The rice samples were extracted by acetonitrile under ultrasonic, and the extract was purified by GPC to remove macromolecular impurities, then followed by LC-MS/MS analysis. The result showed that the recovery was 71.3%- 111.1% with relative standard deviation of 3.64%- 12.76% with spiked level of 0.2 μg. The method was simple and accurate with high automation and extraction efficiency. It was suitable for routine detection of the pesticide residues in rice.

关 键 词：凝胶渗透色谱 LC-MS/MS 农药 大米 

分 类 号：O657.63[理学—分析化学] TS210.7[理学—化学]