藤茶抗菌作用研究进展  

Research progress on antibacterial effects of Ampelopsis grossedentata

作　　者：周茜雅 陈婧 方建国[1] 王文清 

机构地区：[1]华中科技大学同济医学院附属同济医院药学部,湖北武汉430030

出　　处：《中草药》2017年第22期4819-4825,共7页Chinese Traditional and Herbal Drugs

摘　　要：近年来对单味中药、中药提取物、单体化合物以及复方制剂的抑菌实验研究已证实,多种中药均具有较理想的抗菌作用,且不易产生耐药性。民间药食两用藤本植物藤茶富含多种生物功效成分,其中黄酮类成分的量最高,其抗菌活性较好,对耐药菌有抑制作用,并且与抗生素联用时有协同增效作用。综合近10年藤茶抗菌作用的国内外研究进展,对该药用植物的主要抗菌成分、抗菌效果以及作用机制进行整理分析,为藤茶的功效研究、临床应用及产品开发提供借鉴与参考。In recent years, researches on the antibacterial experiments of single herb, extracts, monomer ingredients and the compound preparations have confirmed that a variety of Chinese meteria medica have good antibacterial effects, and they are not easily produced drug resistance. Ampelopsis grossedentata, which can be used as medicine and food, contains various biological ingredients. Among them, flavonoids have desired antibacterial effect and synergistic effect when combined with antibiotics. In this review, antibacterial effects of A. grossedentata were summarized from domestic and foreign study literatures in the recent decade, including the main antibacterial components, the antimicrobial effects, and mechanism of this medicinal plant, aming to provide reference for the studies on the physiological and pharmacological functions, clinical application, and product development of A. grossedentata.

关 键 词：藤茶 二氢杨梅素 黄酮类 抗菌 复方制剂 中药提取物 

分 类 号：R285[医药卫生—中药学]