整合调控技能训练对阿尔海默病患者的康复作用  

The Effects of Integrated Regulation Trainingfor Patients with Alzheimer Disease

作　　者：杨平成 胡美玲 郑伟[3] 冷传芳 陈蕊[4] 向应强[4] 马辛[4] 

机构地区：[1]中国.贵州省铜仁市惠民医院,554300 [2]江西省上饶第五人民医院 [3]广州市脑科医院(广州市惠爱医院,广州医科大学附属脑科医院) [4]首都医科大学附属北京安定医院

出　　处：《中国健康心理学杂志》2017年第11期1617-1619,共3页China Journal of Health Psychology

基　　金：北京市科技计划课题(编号:D101107047810004);首都临床特色应用与研究成果推广(编号:Z15110700400000)

摘　　要：目的:探讨整合调控技能训练对阿尔茨海默病(AD)患者生活质量的影响。方法:本研究设计是随机、开放、前瞻性对照研究。选取符合国际疾病分类第十版(ICD-10)中阿尔茨海默病确诊标准的住院患者共70例,随机分为研究组(常规精神科药物治疗+整合调控技能训练,n=35)和对照组(常规精神科药物治疗+空白对照,n=35),应用世界卫生组织生存质量测定量表简表(WHOQOL-BREF)、匹茨堡睡眠质量指数量表(PSQI)和简明精神病量表(BPRS)在0周,6周末进行盲法评估。结果:干预组和对照组各脱落1例。经6周干预后,研究组在WHOQOL-BREF总分、生理领域、心理领域、社会关系和环境领域得分均低于对照组(t=16.482,4.890,8.308,11.884,6.043;P<0.05)。研究组在PSQI总分、BPRS总分均显著高于对照组(t=3.571,2.025;P<0.05)。结论:整合调控技能训练能够有效的改善AD患者的睡眠质量及生活质量,促进其早日回归社会,值得临床推广应用。Objective：To explore the effect of integrated regulation training（IRT）on quality of life for patients with Alzheimer disease（AD）.Methods：In this randomized controlled, single blind, prospective study, 70 patients with AD who met the edition international classification of diseases（ICD--10）criteria for AD, which were randomly assigned to treatment group（general drugs treatment combined with IRT,n = 35）,and control group（general drugs mono- therapy, n = 35）.We used World Health Organization Quality of Life-- Brief（WHOQOL-- BREF）, Pittsburgh Sleep Quality Index（PSQI）and Brief Psychiatric Rating Scale（BPRS）to blindly assess the efficacy in two groups at 0 and 6 weeks.Results： There was one patient discontinuation between two groups, respectively.In the endpoint of treatment （at 6 weeks）, regarding WHOQOL--BREF total score, physiological factor, psychological factor, and environment factor,there were significantly lower scores in the treatment group when compared with the control group （t = 16.482,4.890,8.308,11. 884,6.043 ; P ~0.05 ）. Furthermore, there were significantly higher scores in the treatment group when compared with the control group on the total score of PSQI and BPRS（t = 3.571,2.025;P〈0.O5）.Con- clusion：Effects of IRT can effectively improve sleep and the quality of life in patients with AD, which will pose a new way to early rehabilitation of AD patients,deserving further clinical applications.

关 键 词：整合调控技能训练 阿尔茨海默病 睡眠 生活质量 

分 类 号：R749.05[医药卫生—神经病学与精神病学]