结直肠神经内分泌瘤33例临床分析及其预后影响  

Clinical Analysis of 33 Cases With Colorectal Neuroendocrine Tumor

作　　者：官申[1] 杨春康[1] 陈泓 卓长华[1] 黄秋艳[1] 吴贤毅[1] 庄咏 

机构地区：[1]福建省肿瘤医院/福建医科大学附属肿瘤医院胃肠肿瘤外科,福建福州350014

出　　处：《中国卫生标准管理》2017年第23期42-44,共3页China Health Standard Management

摘　　要：目的探讨结直肠神经内分泌瘤患者临床特征、诊治方法并分析其影响预后的因素。方法回顾分析福建省肿瘤医院自1988年3月—2014年11月收治的33例结直肠神经内分泌瘤患者的临床资料、手术病理及随访情况。结果 33例结直肠神经内分泌瘤患者经3~82个月不等随访,共发生临床事件数5例,预后与肿瘤大小、浸润深度存在统计学相关性(P<0.01)。结论结直肠神经内分泌瘤早期缺乏典型临床表现,结直肠镜检查活检仍然是诊断的金标准。手术治疗是治愈结直肠神经内分泌瘤的唯一手段,预后与肿瘤大小及浸润深度相关。Objective To investigate the clinical manifestation, diagnosis and treatment of patients with colorectal neuroendocrine tumors in Fujian Cancer Hospital and analyze the factors that affect the prognosis of this disease. Methods The clinical data, surgical pathology and follow-up of 33 patients with colorectal neuroendocrine tumors treated from March 1988 to November 2014 in Fujian Cancer Hospital were analyzed. Results There were 5 cases of clinical events in 33 cases of colorectal neuroendocrine tumor, who were followed up for 3 to 82 months. The prognosis was statistically correlated with tumor size and depth of invasion（P 0.01）. Conclusion The clinical manifestations of colorectal NET are non-special in the early stage. Pathology of Colorectal endoscopy is the golden criterion for diagnosis. Surgical therapy is the only way to cure it. The prognosis was associated with tumor grading, size and depth of infiltration.

关 键 词：结直肠肿瘤 神经内分泌瘤 诊断 预后 

分 类 号：R735[医药卫生—肿瘤]