探讨共聚焦显微镜在感染性角膜炎诊断及疗效判定中的应用  

The Application of in Vivo Confocal Microscopy in the Diagnosis and Treatment of Infectious Keratitis

作　　者：杨海婷[1] 

机构地区：[1]黑龙江省电力医院眼科,黑龙江哈尔滨150030

出　　处：《中国卫生标准管理》2017年第23期75-76,共2页China Health Standard Management

摘　　要：目的研究分析感染性角膜炎使用共聚焦显微镜(in vivo confocal microscopy,IVCM)诊断的价值。方法 2011年3月—2015年3月对我院接收的感染性角膜炎患者98例进行分析,治疗前进行共聚焦显微镜诊断,角膜刮片镜检,真菌培养,然后进行保守治疗,对失败的患者进行角膜移植和眼内容物剜除。患者治疗两周和1个月后分别再次进行共聚焦显微镜诊断。结果接受保守治疗的患者,病原菌平均浸润深度为(64.37±8.85)μm,手术治疗患者的病原菌平均浸润深度为(69.52±9.71)μm。治疗两周后治愈率是0,1个月后的治愈率是67.3%。结论共聚焦显微镜对感染性角膜炎的诊断以及疗效判断具有很高的价值,为临床治疗以及预后分析提供了参考。Objective To study the value of in vivo confocal microscopy（IVCM） in the diagnosis of infectious keratitis. Methods From March 2011 to March 2015, 98 cases of infectious keratitis in our hospital were analyzed. Confocal microscopy, corneal scraping, and fungal culture were performed before treatment, conservative treatment was then performed. The failure of patients with corneal transplantation and orbit evisceration. Confocal microscopy was performed again after two and 1 months of treatment. Results the average infiltration depth of pathogenic bacteria was（64.37 ± 8.85） μm, and the average depth of invasive bacteria was（69.52 ± 9.71） μm in patients receiving conservative treatment. After two weeks of treatment, the cure rate was 0, and the cure rate was 67.3% after 1 months. Conclusion Confocal microscopy is of great value in the diagnosis and judgement of curative effect of infectious keratitis, and provides a reference for clinical treatment and prognosis analysis.

关 键 词：共聚焦显微镜 感染性角膜炎 诊断 

分 类 号：R772[医药卫生—眼科]