光气及神经毒剂类荧光探针的研究进展  

Recent Advances in Phosgene and Nerve Agents Responsive Fluorescent Probes

作　　者：陈建华 李东洋 刘盛华[1] 谭英[2] 尹军[1,2] 

机构地区：[1]华中师范大学化学学院农药与化学生物学教育部重点实验室,武汉430079 [2]清华大学深圳研究生院深圳市化学生物学重点实验室-省部共建国家重点实验室培育基地,广东深圳518055

出　　处：《应用化学》2017年第12期1413-1432,共20页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金(21676113)资助~~

摘　　要：剧毒性光气、神经毒剂对社会安全和人类健康造成了极大的威胁,而传统的检测方法无法在活细胞等微环境体系中对光气、神经毒剂进行检测。荧光探针因其选择性好、灵敏度高、适合于细胞检测等优点而被广泛使用。本文主要综述了近年来在光气、神经毒剂类荧光探针领域所取得的最新研究成果,并对该领域的发展进行了展望。Highly toxic agents, such as phosgene and nerve agents, cause severe threats to public security and humankind. In contrast to traditional ways, the approaches to detect phosgene and nerve agents are expected to be effective detection in vivo. Fluorescent probes have been applied widely in various research fields due to their high selectivity and sensitivity, e recent advances relating to fluorescent probes for developments. xcellent cell permeability and so on. Herein, we review phosgene and nerve agents and prospect their future

关 键 词：荧光探针 光气 神经毒剂 

分 类 号：O657.3[理学—分析化学]