β-CD对胆汁盐类表面活性剂胶束化作用的影响  

Effects of β-CD for Surfactant Micellization of Bile Salts

作　　者：李鑫[1] 罗君 李慎林 

机构地区：[1]湖南师范大学,湖南长沙410006

出　　处：《广州化工》2017年第22期50-55,共6页GuangZhou Chemical Industry

摘　　要：在298.15 K时用电导法、表面张力法研究了β-环糊精(β-CD)与胆汁盐类阴离子型表面活性剂脱氧胆酸钠(NaDC)、胆酸钠(NaC)的包结作用。研究表明:NaDC、NaC与β-CD形成包结物,经最小二乘法拟合,在一定的物质的量浓度范围内临界胶束浓度(CMC)随着β-CD浓度的增大呈线性增加关系。用数学方法计算出β-CD与NaDC、NaC形成1∶1型的稳定包结物的包结常数5450 kg/mol,它将对模拟酶催化具有重要的理论。The influence of β-CD as host molecules on micelle concentration（CMC） of the ionic surfactants（as guest molecules） aqueous systems such as sodium cholate（NaC） and sodiumdeoxycholate（NaDC） were investigated by electro-conductance andsurface tension measurements at 298. 15 K. The experimental results showed that the apparent CMC of NaDC and NaC aqueous systems increased linearly with the increasing of β-CD concentration by least squares fitting. By using mathematical to calculation,the inclusion complex（1 ∶1） of β-CD formed by NaDC and NaC was5450 kg/mol. Moreover,association constants and thermodynamic parameters were calculated,it will have an important theory for simulating enzymatic catalysis.

关 键 词：Β-环糊精 离子型表面活性剂 临界胶束浓度 电导法 表面张力 

分 类 号：O361[理学—流体力学]