不同位置子宫内膜息肉TCRP术后对IVF/ICSI妊娠结局的影响  

Clinical pregnancy outcome in IVF/ICSI treatment following TCRP operation of endometrial polyps in different location

作　　者：马媛[1] 李懋[1] 梁新新[1] 张琬琳[1] 杨弘睚 肖西峰[1] 

机构地区：[1]第四军医大学唐都医院妇产科生殖医学中心,西安710038

出　　处：《生殖医学杂志》2017年第12期1206-1211,共6页Journal of Reproductive Medicine

摘　　要：目的分析不同位置子宫内膜息肉(EPs)患者经宫腔镜子宫内膜息肉电切术(TCRP)后对IVF/ICSI-ET助孕治疗妊娠结局的影响。方法回顾性分析我院生殖医学中心2015年1月至2016年3月明确诊断为EPs、行TCRP治疗的患者的临床资料,按照EPs位置不同分为3组:单纯前壁息肉组(138个周期)、单纯后壁息肉组(148个周期)、前后壁合并息肉组(229个周期),收集3组患者术前、术后及助孕期间的相关变量及指标进行单因素及多元logistic回归分析。结果纳入患者402人次,总计515个IVF/ICSI周期。前后壁合并息肉组的体重指数(BMI)显著高于其他两组,3组间息肉数量比较有显著性差异(P均<0.05)。3组患者胚胎移植时内膜厚度比较有显著性差异(P<0.05)。对3组患者的活产率、临床妊娠率、早产率等妊娠结局进行单因素分析,上述妊娠指标间均无显著性差异(P>0.05)。调整混杂因素后,以单纯前壁息肉组为参照,行多元logistic回归分析,3组患者上述妊娠指标间仍无显著性差异(P>0.05)。结论不同位置EPs患者经TCRP术后行辅助生殖技术助孕治疗对IVF/ICSI-ET的临床妊娠率/活产率均无明显影响。Objective： To assess the clinical pregnancy outcome in IVF/ICSI treatment following transcervical resection of poly（TCRP）of endometrial polyps（EPs）at different location.Methods： The data of the women received IVF/ICSI treatment after TCRP operation from January2015 to March 2016 in the Reproductive Medicine Center of Tangdu Hospital were retrospectively analyzed.All patients were subdivided into three groups according to the different location of EPs：anterior uterine wall（n=138 cycles）,posterior uterine wall（n=148 cycles）and both anterior posterior uterine wall（n =229 cycles）.The basic characteristics,relative parameters and pregnancy outcomes were retrospectively collected.The correlation between the different location of EPs and pregnancy outcomes was analyzed by univariate analysis and multivariate logistic regression.Results： A total of 515 IVF/ICSI treatment cycles of 402 patients were included.The BMI in the group of anterior uterine wall was significantly higher than the other two groups（P0.05）.The number of EPs and the endometrial thickness during embryo transfer were significantly different among the three groups（all P0.05）.The significant differences in clinical pregnancy rate,live birth rate and early abortion rate were not found through univariate analysis and multivariate logistic regression analysis（P0.05）.Conclusions： The clinical pregnancy rate/live birth rate of IVF/ICSI-ET was not significantly affected by TCRP before assisted reproductive technology in patients with EPs at different location.

关 键 词：子宫内膜息肉 宫腔镜 IVF/ICSI 临床妊娠率 活产率 

分 类 号：R0[医药卫生]