艾地苯醌治疗急性脑梗死合并认识功能障碍的临床效果分析  

Study on the Clinical Effects of Idebenone on the Acute Cerebral Infarction Combined with Cognitive Disorder

作　　者：陈炳光 包泽岩 

机构地区：[1]广东三九脑科医院神经内四科,广东广州510510

出　　处：《吉林医学》2017年第12期2283-2284,共2页Jilin Medical Journal

摘　　要：目的:观察分析艾地苯醌治疗急性脑梗死合并认识功能障碍的临床效果。方法:选取40例急性脑梗死合并认识功能障碍患者为研究对象,所有患者随机均分为对照组(n=20)和观察组(n=20)。对照组患者给予降压、调节血脂、改善循环等常规治疗,观察组在常规治疗的基础上,采用艾地苯醌进行治疗。比较两种治疗方法对急性脑梗死合并认识功能障碍患者的临床疗效。结果:治疗后,对照组和观察组的MMSE量表和日常活动能力量表在治疗1个月、2个月、3个月得分均明显优于治疗前,差异有统计学意义(P<0.05);观察组MMSE量表和日常活动能力量表得分在治疗1个月、2个月、3个月得分均优于对照组,差异有统计学意义(P<0.05),且认识功能障碍改善总有效率高于对照组,差异有统计学意义(P<0.05)。结论:艾地苯醌能够有效地改善急性脑梗死合并认识功能障碍患者的神经症状及功能障碍,具有临床推广价值。Objective To study the clinical effects of Idebenone in the treatment of acute cerebral infarction combined with cognitive disorder. Method 40 patients with acute cerebral in farction cambined with cognitive disoroler were selected as the research object,they were randomly divided into control group（n = 20） and observation group（n = 20）. The control group was given conventional therapy which included anti-hypertension,regulating blood lipids,improving blood circulation,while observation group was given the same conventional therapy and Idebenone. The clinical effects were compared between two groups. Results In1 st,2 nd and 3 th month after operation,the score of MMSE and Barthel in two groups became better（P〈0. 05）,and the observation group was better than control group（P〈0. 05）. The total effective rate of observation group was higher than control group（P〈0. 05）. Conclusion Idebenone can improve neurological sign and dysfunction in the treatment and it has clinical value.

关 键 词：艾地苯醌 急性脑梗死 功能障碍 临床疗效 

分 类 号：R743.33[医药卫生—神经病学与精神病学]