脑梗塞患者体外模拟血栓试验的研究  

The Changes of Imitating Thrombosis-test in Vitro for the Cerebral Infarction Patients

作　　者：罗乐宣 罗国辉[2] 陆泽元 魏文斌 邝碧娟[2] 张国良[2] 黄建平 曾莲意 

机构地区：[1]广东省深圳市福田区卫生局,518033 [2]广东医学院深圳心肾疾病研究所 [3]深圳市福田人民医院内科

出　　处：《中国微循环》2002年第4期224-225,共2页Journal of Chinese Microcirculation

摘　　要：目的探讨脑梗塞病人的体外模拟血栓试验的意义。方法用标准摆动式旋转CAST法对深圳市43例脑梗塞患者和51例健康人进行体外模拟血栓指数的试验 ,并对30例患者用降纤酶治疗和治疗前后进行比较。结果患者模拟血栓湿重和指数Q值与健康人有显著差异 (P<0.05) ,血栓长度改变不明显 (P>0.05) ;用降纤酶治疗前后 ,血栓长度、湿重均有显著性改变 (P<0.05)、Q值有极显著性改变 (P<0.01)。Objective To investigate the changes of imitating thrombosis-test (ITT) in vitro for the cerebral infarction patients.Methods ITT was measured in the 43 cerebral infarction cases and 51 healthy controls. The ITT before defibrase was injected in 30 cerebral infarction cases compared with that after treatment.Results The weight of imitating thrombosis and thrombus index Q of the cerebral infarction group is highter than that in control group (P<0.05), but there is no signficant difference in the length of thrombus between two groups(P>0.05). The length, weight of thrombus and the thrombus index Q were remarkably lower in treatment group with defibrase (P<0.01).Conclusions ITT is a useful way in assessing the situation of thrombus formation in vitro.

关 键 词：脑梗塞 体外模拟血栓试验 血栓指数Q 降纤酶 溶栓治疗 血栓形成 

分 类 号：R743.33[医药卫生—神经病学与精神病学]