HSP70抗体检测在缺血性脑卒中患者病因学分型中的应用  

Application of HSP70 Antibody Detection in Etiological Typing of Patients With Ischemic Stroke

作　　者：高展[1] 祝鸿雁[1] 赵丽波[1] 

机构地区：[1]黑龙江省医院老年神经内科,黑龙江哈尔滨150036

出　　处：《中国卫生标准管理》2017年第26期46-48,共3页China Health Standard Management

摘　　要：目的研究缺血性脑卒中患者接受HSP70抗体检测并进行病因学分型的临床效果,为临床早期诊断和治疗提供参考。方法将2017年1—12月我院收治的150例缺血性脑卒中患者进行研究分析,选取30例健康体检者作为对照组,测定HSP70水平。研究分析患者病因分型和HSP70抗体水平的关系。结果大动脉粥样硬化型和小动脉闭塞型患者的HSP70水平比其他类型高,大动脉粥样硬化型、小动脉闭塞型、心源性栓塞型HSP70水平比对照组高,不明原因型和其他病因型的HSP70水平和对照组比较,差异无统计学意义(P>0.05)。结论HSP70在初发的缺血性脑卒中患者中水平较高,复发患者比初发患者高,可以将其作为患者预后的判断依据。Objective To study the clinical effect of HSP70 antibody detection in etiological typing in patients with ischemic stroke,so as to provide reference for early diagnosis and treatment of ischemic stroke.Methods From January to December 2017,150 cases of ischemic stroke patients in our hospital were analyzed,and 30 healthy people were selected as control group,and the level of HSP70 was measured.The relationship between etiology classification and HSP70 antibody level was studied.Results The HSP70 level in patients with large artery atherosclerosis type and small artery occlusion type was higher than patients with other types,the HSP70 level in patients with large artery atherosclerosis type,small arteriolar occlusion type and cardioembolism type was higher than that in control group,and the difference of HSP70 level between unexplained type or other causes type and that in control group had no statistic significant（P〈0.05）.Conclusion The level of HSP70 in patients with initial ischemic stroke is higher,which is higher in recurrence patients than the initial patients,which can be used as the basis for judging the prognosis of the patients.

关 键 词：缺血性脑卒中 TOAST分型 HSP70抗体 

分 类 号：R742[医药卫生—神经病学与精神病学]