能谱CT在肺结节或肿块诊断中的应用  

Application of spectral CT in the diagnosis of pulmonary nodules or masses

作　　者：范恒鑫 陈盈 樊树峰 杨海 谢继承 

机构地区：[1]温州医科大学附属台州医院放射科,浙江临海317000 [2]浙江中医药大学附属第二医院放射科,浙江杭州310000

出　　处：《实用放射学杂志》2017年第12期1836-1839,共4页Journal of Practical Radiology

基　　金：浙江省自然科学基金项目（LY13H180010）;浙江省医药卫生基金项目（2013KYA223）;台州市科技局A类项目（121KYA08）.

摘　　要：目的 探讨能谱CT多参数分析在肺结节或肿块诊断中的价值。方法 对319例经病理和/或随访证实的肺结节或肿块的CT增强动脉期能谱资料进行回顾性分析，分为炎症、肺癌与结核3组。分别测量动脉期碘基值、水基值、有效原子序数及60、70、80 keV单能量图像CT值。采用单因素方差分析、LSD-t检验比较3组参数的差异。结果 单因素方差分析示3组间的碘基值、水基值、有效原子序数及60、70、80 keV单能量图像CT值的差异均有统计学意义（P〈0.05）。LSD-t检验示炎症组与结核组、炎症组与肺癌组间的碘基值和有效原子序数的差异有统计学意义（P＜0.05）；肺癌组与炎症组、肺癌组与结核组间的水基值差异有统计学意义（P〈0.05）；60、70、80 keV各单能量图像的CT值，在结核组与炎症组、肺癌组间的差异有统计学意义（P〈0.05）。结论 CT增强动脉期能谱多参数分析有助于肺结节或占位的诊断和鉴别诊断。Objective To investigate the value of multiple parameter analysis in spectral CT scanning for the diagnosis of pulmonary nodules or masses.Methods The spectral CT scanning data in arterial phase of 319 patients with pulmonary nodules or masses confirmed by pathology and/or follow-up were analyzed retrospectively.The patients were divided into 3 groups：inflammatory group, lung cancer group and tuberculosis group. The Iodine [water） concentration, water （Iodine） concentration, the effective atomic number and the CT value of 60,70 and 80 keV single energy in the leisons were measured.One way ANOVA and LSD-t test were used for statistical analysis.Results One way ANOVA showed that the Iodine （water） concentration,water [Iodine） concentration, the effective atomic number and the CT value of 60,70 and 80 keV single energy among 3 groups in the arterial phase were all statistically different （P〈0.05}.The LSD-t test showed there were statistical differences of Iodine content and effective atomic number between tuberculosis group and inflammatory group, lung cancer group and inflammation group （ P〈 0.05 ）. There were statistical differences between tuberculosis group and lung cancer group,inflammation group and lung cancer group in water concentration （P〈0.05 ）.The statistical differences in CT value of 60,70 and 80 keV single energy between tuberculosis group and inflammatory group,inflammation group and tuberculosis group were also found（P〈0.05）. Conclusion Multiple parameter analysis of spectral CT scanning in arterial phase could attribute to the diagnosis and differential diagnosis of pulmonary nodules or masses.

关 键 词：肺肿瘤 计算机体层成像 

分 类 号：R734.2[医药卫生—肿瘤] R814.42[医药卫生—临床医学]