广州市天河区18-24月龄儿童孤独症筛查及影响因素  

Prevalence and the risk factors of autism among 18~24 months old children in Guangzhou Tianhe district

作　　者：卜丽娟 陈凯云[2] 岑超群[2] 谢宁 邹小兵[2,1] 

机构地区：[1]广州市天河区妇幼保健院,广东广州510620 [2]中山大学附属第三医院,广东广州510630

出　　处：《热带医学杂志》2017年第11期1532-1534,1560,共4页Journal of Tropical Medicine

基　　金：天河区科技计划项目(2013KW037)

摘　　要：目的了解广州市天河区18~24月龄儿童孤独症流行情况和危险因素。方法选取2014年11月-2015年10月在广州市天河区妇幼保健院体检的18~24月龄儿童,采用婴幼儿孤独症筛查量表(CHAT-23)进行调查研究,分析孤独症筛查情况和危险因素。结果共回收合格调查表1 567份,孤独症筛查复筛阳性率1.7%(27/1 567),男女检出率比4∶1,女性(OR=0.223,95%CI:0.064~0.774)、父亲性格外向(OR=0.196,95%CI:0.055~0.704)是孤独症筛查阳性的保护因素,靠祖辈教育(OR=3.235,95%CI:1.324~7.907)、放任不管(OR=6.296,95%CI:1.530~25.903)和打骂(OR=3.534,95%CI:1.092~11.439)是孤独症筛查阳性的危险因素。结论家人的陪伴、父亲性格的影响及积极的教育方式,对减少儿童孤独症发生有着重要作用。Objective To understand the prevalence and risk factors of autism among 18~24 months old children in Guangzhou Tianhe district. Methods Children at the age of 18 to 24 months who had gotten physical examinations in Maternal and Child Health Hospital of Guangzhou Tianhe district were selected for the study. Autism screening and its risk factor was performed by using the checklist for autism intoddlers-23（CHAT-23）. Results A total of 1567 cases of children were investigated. The positive rate of autism was 1.72%（27/1567）,and the ratio of male to female was 4：1. Female（OR=0.223,95%CI：0.064~0.774）and father′s extroversion（OR=0.196,95%CI：0.055~0.704）were protective factors of autism. Being educated by the grandparents（OR=3.235,95%CI：1.324~7.907）,indulgence（OR=6.296,95%CI：1.530~25.903）and beating（OR=3.534, 95%CI：1.092~11.439）were the risk factors for autism. Conclusion The accompany of families,the influence of father＆#39;s characters and positive ways of education have a great influence in reducing the incidence of childhood autism.

关 键 词：孤独症 患病率 影响因素 儿童 

分 类 号：R749.94[医药卫生—神经病学与精神病学]