术中矩阵式电极的精确定位研究  

Study on precise localization of intraoperative matrix electrode

作　　者：姜涛[1] 胡欢 符琼琳 白红民[2] 

机构地区：[1]华南理工大学生物医学工程系,广州510006 [2]广州军区广州总医院,广州510010

出　　处：《生物医学工程学杂志》2017年第6期958-962,共5页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(81201014);广东省科技厅资助项目(2014A020215005;2014A020216006);广东省自然科学基金资助项目(10151001002000010)

摘　　要：为精确定位术中硬膜下矩阵式电极的图像坐标和序号,本文提出一种图像处理的矩阵式电极定位联合算法。采用电极逐点扩展定位算法,向上下左右逐点扩展,确定各个电极初始坐标和序号;采用单电极坐标区域提取算法,确定各个电极最佳坐标,从而逐点定位所有电极的图像坐标和序号。本文研究结果表明,电极序号定位准确率达100%,电极坐标定位误差小于2 mm。本文研究的算法可以精确定位呈弧形排列的矩阵式电极图像坐标和序号,从而辅助绘制大脑皮层功能映射图,实现术中脑功能区精确定位,因此今后或可广泛应用于基于皮质脑电信号分析的神经系统科学研究和应用。In order to accurately localize the image coordinates and serial numbers of intraoperative subdural matrix electrodes, a matrix electrode localization algorithm for image processing is proposed in this paper. Firstly, by using point-by-point extended electrode location algorithm, the electrode is expanded point-by-point vertically and horizontally, and the initial coordinates and serial numbers of each electrode are determined. Secondly, the single elec- trode coordinate region extraction algorithm is used to determine the best coordinates of each electrode, so that the image coordinates and serial numbers of all electrodes are determined point-by-point. The results show that the positioning accuracy of electrode serial number is 100%, and the electrode coordinate positioning error is less than 2 mm. The algori- thms in this paper can accurately localize the image coordinates and the serial numbers of a matrix electrode arranged in an arc, which could aid drawing of cortical function mapping, and achieve precise positioning of brain functional areas, so that it can be widely used in neuroscience research and clinical application based on electrocorticogram analysis.

关 键 词：矩阵式电极 图像处理 坐标定位 功能映射图 术中脑功能定位 

分 类 号：R741.044[医药卫生—神经病学与精神病学] TP391.41[医药卫生—临床医学]