荆花胃康胶丸联合质子泵抑制剂和抗生素调治Hp相干消化性溃疡的Meta分析  

Meta-analysis of Jinghua Weikang Pills Combined with Proton Pump Inhibitors and Antibiotics in Treating Hp-positive Peptic Ulcer

作　　者：岳苏阳 丁钦[2] 闾永健 徐茜 吴克俭 

机构地区：[1]徐州医科大学附属医院,徐州221002 [2]淮安市第二人民医院,淮安223001

出　　处：《世界中医药》2017年第11期2831-2834,共4页World Chinese Medicine

摘　　要：目的:评估中成药荆花胃康胶丸结合质子泵抑制剂以及抗生素调治Hp相干消化性溃疡的临床效果,为今后病患的适当用药提供参考。方法:使用Pub Med、维普、中国知网以及万方数据对关联文献进行查找,并采用Rev Man 5.3软件进行分析。结果:共有18篇文献纳入统计,共涉及治疗总数2 177例。实验组的总有效率[OR=6.35,95%CI(4.05,9.93),P<0.05]、Hp根除率[OR=3.41,95%CI(2.63,4.41),P<0.05]以及溃疡愈合率[OR=2.82,95%CI(2.14,3.71),P<0.05]均优于对照组。结论:实验组在调治Hp相干消化性溃疡方面要优于对照组。Objective： To evaluate the efficacy of Chinese medicine Jinghua Weikang Pills combined with proton pump inhibitors and antibiotics in the treatment of Hp-Positive peptic ulcer and provide reference for medication. Methods： Related literatures were searched through Pub Med,VIP Information and Wanfang Data,and analyzed by Rev Man 5. 3 software. Results： According to the inclusion and exclusion criteria,a total of 18 literatures were included in the study,involving a total of 2 177 therapists. The results of meta-analysis showed： The total effective rate of the experimental group was better than that of the control group（ OR = 6. 35,95%CI（ 4. 05,9. 93）,P 0. 05）. The curative rate of helicobacter pylori in the experimental group was better than that of the control group（ OR = 3. 41,95% CI（ 2. 63,4. 41）,P 0. 05）. The healing rate of ulcer in the experimental group was better than that of the control group（ OR = 2. 82,95% CI（ 2. 14,3. 71）,P 0. 05）. Conclusion： Experimental group in the treatment of Hp-positive Peptic Ulcer is better than that of the control group.

关 键 词：荆花胃康 质子泵抑制剂 抗生素 消化性溃疡 

分 类 号：R573.1[医药卫生—消化系统]