精准肝中叶切除20例临床研究  

Precise Liver Resection for Hepatocellular Carcinoma:A Report of 20 Cases Receiving Mesohepatectomy

作　　者：何忠野 尚海 郝志强 傅熙博 马作红 冯照强 李文心 王坤 王鑫 华向东 

机构地区：[1]中国医科大学肿瘤医院辽宁省肿瘤医院,辽宁沈阳110042

出　　处：《肿瘤学杂志》2017年第11期1011-1015,共5页Journal of Chinese Oncology

基　　金：十二五国家科技惠民计划项目(S2013GMB000019);辽宁省科学技术计划项目(2015225001);辽宁省科技厅科技攻关项目(2012225016)

摘　　要：[目的]评价精准肝切除手术方式在肝中叶肝细胞癌切除术中的临床价值。[方法]回顾性分析辽宁省肿瘤医院2010年6月至2015年6月间施行的原发性肝细胞肝癌肝脏中叶切除的手术病例45例。精准肝切除组20例;Pringle法第一肝门阻断肝脏不规则切除25例。[结果]精准肝切除组对肝功能影响小,手术并发症少,术后并发症发生率为5%(1/20),而对照组术后并发症发生率为36%(9/25)(P<0.05)。两组1年复发率比较无统计学差异(P>0.05)。[结论 ]精准肝切除手术方式具有更好的手术可控性和手术安全性,对肝功损伤小,在肝脏中叶切除手术中值得推广。[Objective] To evaluate the clinical value of precise hepatectomy for hepatocellular carcinoma in the central region of the liver. [Methods] Forty-five 45 cases with primary hepatocellular carcinoma in Liaoning Provincial Cancer Hospital between June,2010 and June,2016 were studied retrospectively. Precision liver resection was performed in 20 patients（experimental group） while irregular resection of liver by blocking the first hepatic portal with Pringle method was done in 25（control group）. Clinical data of the two groups were compared. [Results] Postoperative complication rate was significantly lower in the precise hepatectomy group（5%;1/20） than in the control group（36%;9/25）（P〈0.05）. There was no significant difference in the recurrence rate of hepatocellular carcinoma between the two groups（P〉0.05） [Conclusion] Precise hepatectomy is more manageable and safer,and results in milder liver damage. It is worth popularizing as a form of mesohepatectomy.

关 键 词：精准肝切除 肝中叶切除手术 原发性肝细胞癌 

分 类 号：R735.7[医药卫生—肿瘤]