肝癌患者肝脏部分切除术后感染的影响因素分析  

Analysis of influencing factors for infections after partial hepatectomy in patients with liver cancer

作　　者：李辉[1] 于淼[2] 刘成科 石合现 孔杰 

机构地区：[1]菏泽市立医院肝胆外科,山东菏泽274000 [2]菏泽医学专科学校药理学教研室,山东菏泽274000

出　　处：《中华医院感染学杂志》2017年第24期5611-5614,共4页Chinese Journal of Nosocomiology

基　　金：菏泽市医药卫生科研基金资助项目(2009-0874)

摘　　要：目的探究肝癌患者肝脏部分切除术后感染发生的影响因素。方法选取2015年1月-2017年6月医院收治的400例行部分肝脏切除术的肝癌患者为研究对象,按照术后是否发生感染分为感染组98例和未感染组302例;分析比较两组患者的临床基本资料,术前检查结果及手术过程指标。结果与未感染组相比,感染组患者中年龄≥60岁、合并糖尿病、白蛋白含量<35g/L的概率高于对照组(P<0.05);感染组患者的手术时间≥300min、术中出血量≥400mL、引流管放置时间≥7d的构成比高于未感染组(P<0.05);多因素Logistic回归分析结果显示,患者年龄、术前糖尿病史、低白蛋白水平、手术时间、术中出血量及引流管放置时间能够影响肝癌患者肝脏部分切除术后并发感染(P<0.05)。结论肝癌患者部分肝脏切除术后并发感染的相关因素较多,对影响因素给予相应的预防措施,对减少术后感染的发生,有一定的作用。OBJECTIVE To explore the influencing factors for infections after partial hepatectomy in patients with liver cancer.METHODS A total of 400 patients with hepatocellular resection were selected from Jan.2015 to Jun.2017.According to whether the infections occurred after operation,the patients were divided into infected group（98 cases）and uninfected group（302 cases）.The basic clinical data,preoperative examination results and surgical process indicators between the two groups of patients were compared.RESULTS Compared with uninfected group,the number of patients with age≥60,complicated with diabetes and reoperative albumin content〈35 g/L of infected group was significantly higher.The constituent ratio of patients with operation time≥300 min,intraoperative blood loss≥ 400 mL,and drainage tube placement time≥7 din infected group was higher than that in uninfected group（P〈0.05）.Multivariate logistic regression analysis showed that,the age,preoperative diabetes history,low albumin content,operation time,intraoperative bleeding and drainage tube placement time could lead to infection in patients after partial hepatectomy（P〈0.05）.CONCLUSIONThere are many related factors of concurrent infections after partial hepatectomy in patients with hepatocellular carcinoma.It has a certain role to give the corresponding preventive measures on the influencing factor to reduce postoperative infections.

关 键 词：肝癌 肝脏部分切除术 感染 影响因素 

分 类 号：R735.7[医药卫生—肿瘤]