消栓颗粒联合阿托伐他汀治疗脑梗死临床观察  

Clinical observation of therapeutic effect of Xiaoshuan granules combined with atorvastatin in patients with cerebral infarction

作　　者：莫汉维[1] 黄向华[1] 邓树荣[1] 梁涛[1] 麦海芬 钟雪[1] 

机构地区：[1]贵港市中西医结合骨科医院,广西贵港537100

出　　处：《中国实用神经疾病杂志》2017年第21期34-36,共3页Chinese Journal of Practical Nervous Diseases

基　　金：广西贵港市科学研究与技术开发计划项目(编号:1504018)

摘　　要：目的探讨消栓颗粒联合阿托伐他汀对脑梗死患者颈动脉粥样硬化的影响。方法选取2015-01-2017-01贵港市中西医结合骨科医院收治的脑梗死患者225例,随机分为3组,分别予消栓颗粒(中成药组)、阿托伐他汀(西药组)及两种药物联合治疗(联合治疗组)。结果联合治疗组肢体偏瘫的症状改善总有效率明显高于其他2组,颈动脉内-中膜厚度、动脉粥样硬化斑块面积改善均明显优于其他2组。结论消栓颗粒联合阿托伐他汀能有效改善脑梗死患者的临床症状,也能改变颈动脉粥样硬化的状况,有效改善颅内供血情况,相比单药治疗更有效,适合临床推广。Objective To investigate the therapeutic effect of Xiaoshuan granules combined with atorvastatin in carotid atherosclerosis in patients with cerebral infarction. Methods Totally 225 patients with cerebral infarction admitted in our hospital from January 2015 to January 2017 were randomly divided into three groups： Xiaoshuan granules （Chinese medicine group）, atorvastatin （western medicine group） and two combination therapy （combination therapy group）. Results In the combined treatment group,the total effective rate of limb herniplegia was significantly higher than that of the other two groups. The improvement of carotid intima-media thickness and atherosclerotic plaque area were better than that of the other two groups. Conclusion Xiaoshuan granules combined with atorvastatin can effectively improve the clinical symptoms of patients with cerebral infarction, but also can change the status of carotid atherosclerosis,effectively improve intracranial blood supply. It is more effective than monotherapy and is suitable for clinical promotion.

关 键 词：消栓颗粒 阿托伐他汀 脑梗死 颈动脉内-中膜厚度 动脉粥样硬化斑块 

分 类 号：R743.33[医药卫生—神经病学与精神病学]