腹腔镜治疗大于5cm胃肠间质瘤的临床疗效与安全性分析  

Clinical efficacy and safety of laparoscopic surgery in treating gastrointestinal stromal tumors larger than 5cm

作　　者：王荣 徐勇[2] 

机构地区：[1]中铁一局集团中心医院普外科,陕西渭南714100 [2]西安高新医院普外科,西安710075

出　　处：《中华普外科手术学杂志（电子版）》2017年第6期482-484,共3页Chinese Journal of Operative Procedures of General Surgery(Electronic Edition)

摘　　要：目的探讨腹腔镜治疗肿瘤>5 cm的胃肠间质瘤的临床疗效。方法回顾性分析2010年1月至2012年1月40例胃肠间质瘤患者的临床资料,根据术式不同分为腹腔镜组和开腹手术组,各20例。利用SPSS19.0统计学软件进行分析,两组患者术中术后各项指标用(x珋±s)表示,应用独立样本t检验;并发症发生率采用χ2检验;5年生存率根据Kaplan-meier法计算并绘制生存曲线,P<0.05差异有统计学意义。结果腹腔镜组手术时间明显长于开腹组(P=0.034);但术中出血量、术后引流量、肠道恢复时间、住院时间明显少于开腹组,两组差异均有统计学意义(P<0.05)。术后并发症及5年总生存率比较,两组差异无统计学意义(P>0.05)。结论腹腔镜治疗肿瘤>5 cm的胃肠间质瘤在手术时间上略长于开腹手术,但是术中出血量及术后引流量较少,术后恢复快,值得临床推广。Objective To evaluate the clinical efficacy and safety of laparoscopic surgery in treating gastrointestinal stromal tumors larger than 5 cm. Methods Clinical data of 40 cases patients with gastrointestinal stromal tumors were analyzed retrospectively , who received laparoscopic surgery during 2010.01 to 2012.01.All patients were randomly divided into laparoscopic group （ 20 cases ） and open laparotomy group （20 cases）.Statistical analysis were performed by using SPSS 19.0 software.Measurement data, such as perioperative indicators were expressed as （x-＆#177;s） and were examined by t test.Count data such as postoperative complications rate were examined by chi square test, Kaplan-meier was used to calculate and draw the survival curve within 5 years.A P value of 〈0.05 was considered as statistically significant.Results The operation time in laparoscopic group was significantly longer than that in laparotomy group （P=0.034 ）, however the intra-operative blood loss ,postoperative drainage amount, the intestinal recovery time were less than those in laparotomy group, with significant difference （P〈0.05）.There were no significant difference between both 2 groups, in terms of postoperative complications and 5 year overall survival （ P〉0.05）. Conclusions The operation time of laparoscope might be longer than that of laparotomy, but the intra-operative blood loss and postoperative drainage amount would be less.with quicker recovery, which is worth of clinical promotion.

关 键 词：胃肠道间质肿瘤 腹腔镜检查 存活率分析 

分 类 号：R735[医药卫生—肿瘤]