卒中后早期CT值与预后抑郁指数及神经功能的相关性  

The Correlation of Early CT Value with Post-stroke Depression Index and Neurological Function

作　　者：张锋[1] 徐英进[2] 李冰[3] 辛伟凡 魏巍[4] 

机构地区：[1]河北省第六人民医院放射科,河北保定071000 [2]河北大学附属医院CT/MRI室 [3]河北省第六人民医院物质依赖科 [4]河北省荣军医院放射科

出　　处：《中国健康心理学杂志》2017年第12期1815-1818,共4页China Journal of Health Psychology

摘　　要：目的:探讨缺血性脑卒中后早期CT值预后抑郁指数及神经功能的相关性及临床意义。方法:选取2014年6月-2016年3月因缺血性脑卒中于我院住院的患者共89例,根据预后是否发生抑郁分为抑郁组(PSD)和非抑郁组,记录所有患者卒中部位的CT值,采用抑郁自评量表(SDS)和神经功能缺损评分(NDS)评价患者的神经功能,采用SPSS 24.0对其结果进行相关分析。结果:PSD组和非PSD组患者病变部位比例比较差异无统计学意义,PSD组患者卒中后2w、1m和3m的抑郁指数显著高于非PSD组(t=7.083,10.369,13.866;P<0.05),PSD组患者在卒中后1m和3m的HAMD评分显著高于非PSD组(t=7.758,11.027;P<0.05),其中PSD组的平均CT值为(23.4±2.5)HU,非PSD组的CT值为(28.4±2.8)HU,PSD组显著低于非PSD组,差异具有统计学意义(t=-8.717,P<0.05),卒中后3个月PSD组的NIHSS显著高于非PSD组(t=5.262,P<0.05)而ADL分低于非PSD组(t=-7.330,P<0.05),缺血性脑卒中早期CT值和抑郁指数显著的负相关(r=-0.477,P=0.016),与HAMD评分存在显著的负相关(r=-0.526,P=0.004),与NIHSS评分存在显著的负相关(r=-0.487,P=0.001),与ADL评分存在显著的正相关(r=0.503,P<0.001)。结论:缺血性脑卒中早期的CT值与抑郁指数和神经功能呈负相关,对卒中后PSD的发生具有一定的预测作用。Objective：To study the correlation and its clinical significance of post-stroke depression index of early CT value after post stroke and neurological function.Methods：A total of 89 cases in our hospital were selected from June 2014 to March 2016.According to the prognosis that whether happen post-stroke depression,the patients were divided into the depression group and the non-depression group;we recorded all parts of CT value in the stroke patients and used self-rating depression scale（SDS）and neural function defect score（NDS）to evaluate the patient＇s neurologic function,and used SPSS 24.0 correlation analysis on the result.Results：The proportion of pathological changes of patients with PSD and the non-PSD group had no statistically significant difference.After stroke 2 w,1 m and 3 m＇s,depression index in PSD patients was significantly higher than those of the non-PSD group（t=7.083,10.369,13.866;P0.05）,the HAMD scores of the PSD group after stroke for 1 mand 3 m were significantly higher than those in the non-PSD group（t=7.758,11.027;P0.05）,the average CT value of PSD was significantly lower than that of the non-PSD（t=-8.717,P0.05）,the NIHSS of the PSD group after stroke for 3 months was significantly higher than that of the non-PSD group（t=5.262,P0.05）,and ADL score was significantly lower in the PSD group than the non-PSD group（t=-7.330,P0.05）,the early CT value of ischemic cerebral apoplexy and depression index had a negative correlation（r=-0.477,P=0.016）,there was a significant negative correlation between CT value and HAMD score（r=-0.526,P0.01）,there was a significant negative correlation between CT value and NIHSS score（r=-0.487,P0.01）,and a positive correlation between CT value and ADL scores（r=0.503,P0.001）.Conclusion：The early CT value of ischemic cerebral apoplexy is negatively correlated with depression index and neural function,and has a certain prediction effect to the occurrence of PSD after stroke.

关 键 词：缺血性脑卒中 CT值 抑郁指数 神经功能 

分 类 号：R749.92[医药卫生—神经病学与精神病学]