美蓝局部染色乳腺癌哨兵淋巴结病理分析  

Pathologic analysis of sentinel lymph nodes with Methylene

作　　者：巩涛[1] 邢颖[1] 王跃欣[1] 曹文庆[1] 孙靖中[1] 

机构地区：[1]河北省人民医院腺体外科,河北石家庄050051

出　　处：《第四军医大学学报》2002年第16期F002-F002,共1页Journal of the Fourth Military Medical University

摘　　要：AIM To validate the feasibility and metastasis of sentinel lymph node (SLN) in breast carcinoma. METHODS SLNs in breast carcinoma were dyed by methylene blue. All SLNs and nosentinel lymph nodes (NSLNs) were subjected to routine H&E histology. The patients with negative axillary lymph nodes were deeply evaluated by serial sections and immunohistochemical analysis to locate occult metastases. RESULTS SLN was identified in 30 of 35 patients (85.7%). Metastases were identified in 39.2% of SLNs and 11.3% of NSLNs. The odds were 5.1 times higher that metastases were detected in SLNs compared with NSLNs. Occult metastases were identified in 19.4% of SLNs and 2.2% of NSLNs. The odds were 10.7 times higher that occult metastases were be detected in SLNs compared with NSLNs. CONCLUSION SLN can predict presence or absence of axillary node metastases.AIM To validate the feasibility and metastasis of sentinel lymph node (SLN) in breast carcinoma. METHODS SLNs in breast carcinoma were dyed by methylene blue. All SLNs and nosentinel lymph nodes (NSLNs) were subjected to routine H&E histology. The patients with negative axillary lymph nodes were deeply evaluated by serial sections and immunohistochemical analysis to locate occult metastases. RESULTS SLN was identified in 30 of 35 patients (85.7%). Metastases were identified in 39.2% of SLNs and 11.3% of NSLNs. The odds were 5.1 times higher that metastases were detected in SLNs compared with NSLNs. Occult metastases were identified in 19.4% of SLNs and 2.2% of NSLNs. The odds were 10.7 times higher that occult metastases were be detected in SLNs compared with NSLNs. CONCLUSION SLN can predict presence or absence of axillary node metastases.

关 键 词：美蓝染色 乳腺癌 哨兵淋巴结 病理 

分 类 号：R737.9[医药卫生—肿瘤]