急性脑病伴双向发作及后期弥散降低  

Acute encephalopathy with biphasic seizures and late reduced diffusion

作　　者：杨立彬[1] 吴雪梅[1] 梁建民[1] 

机构地区：[1]吉林大学第一医院小儿神经科,长春130021

出　　处：《中华实用儿科临床杂志》2017年第24期1853-1858,共6页Chinese Journal of Applied Clinical Pediatrics

基　　金：吉林省卫生计生委项目（20102030）;吉林省自然科学基金（白求恩专项,20160101123JC）;吉林省省级产业创新专项资金项目（2017C029-1）;吉林大学第一医院儿科发展基金

摘　　要：急性脑病（acute encephalopathy）是儿童期，尤其在婴幼儿期神经系统较常见疾病。急性脑病伴双向发作及后期弥散降低（acute encephalopathy with biphasic seizures and late reduced diffusion，AESD）是其中的新亚型，为伴热性惊厥持续状态、远期认知损害及局部脑萎缩的急性脑病，可伴有远期严重认知功能损害。额叶受累为主的急性婴儿期脑病（acute infantile encephalopathy predominantly affecting the frontal lobes，AIEF）被视为AESD的特殊亚型，受累部位主要在额叶。提高对儿童急性脑病的认识，尽早做出诊断具有重要意义。Acute encephalopathy is a common childhood disease, especially in the nervous system of intants and young children. Recently, a new subtype of childhood acute encephalopathy named acute encephalopathy with bi- phasic seizures and late reduced diffusion （ AESD ） has been reported. The patients present with persistent febrile sei- zures,long - term cognitive impairment and local brain atrophy. Acute infantile encephalopathy predominantly affecting the frontal lobes is a special type of AESD, which mainly impair the frontal lobe the irrlprovement of understanding and early diagnosis of acute encephalopathy in children is particularly important.

关 键 词：急性脑病 热性惊厥持续状态 认知损害 

分 类 号：R742[医药卫生—神经病学与精神病学]