重度颈动脉狭窄支架植入术远期效果评价  

Long term effect of stent implantation in patients with severe carotid stenosis

作　　者：吴志强[1] 李润雄[1] 罗根培[1] 王世芳[1] 

机构地区：[1]广东省东莞市人民医院神经内科,523000

出　　处：《实用医学杂志》2017年第24期4102-4104,共3页The Journal of Practical Medicine

基　　金：广东省东莞市科技局立项课题(编号:201015000076)

摘　　要：目的探讨重度颈动脉狭窄支架植入术远期效果。方法回顾2009年1月至2015年12月在本科住院治疗的66例重度颈动脉狭窄患者的临床资料,其中40例患者行颈动脉狭窄支架植入术治疗(作为研究组),26例患者常规药物治疗(作为参照组),随访36个月,采用SF-36评价患者生存质量,通过随访记录患者脑血管事件发生率。结果研究组术后3、12、24、36个月的生存质量评分均高于参照组,且差异显著(P<0.05);研究组院后12、24、36个月的脑血管事件发生率均低于参照组,且差异显著(P<0.05)。结论应用颈动脉狭窄支架植入术治疗重度颈动脉狭窄的远期效果明显,可有效提高患者院后生存质量,降低患者脑血管事件发生率。Objective To investigate the long term effect of stent implantation for severe carotid stenosis. Methods The clinical data of 66 patients with severe carotid artery stenosis who were hospitalized from January 2009 to December 2015 were retrospectively reviewed.40 patients underwent carotid artery stenosis stent implanta-tion（as study group）and 26 patients were treated with conventional drug theraphy（as control group）.All patient were followed up for 36 months.and the quality of life of the patients was evaluated by SF-36 and the incidence of cerebrovascular events was recorded by following up.Results The quality of life score of the study group were sig-nificantly higher than those of the control group at 3 months,12 months,24 months and 36 months after operation （P〈0.05）;the incidence of cerebrovascular events after 12 months,24 months and 36 months in the study group was lower than in the control group,and the difference was significant（P〈0.05）.Conclusions There is obvious long-term effect of carotid artery stenting in the treatment of severe carotid stenosis,in which the quality of life can be effectively improved and the incidence of cerebrovascular events can be reduced in patients with carotid stenosis.

关 键 词：重度颈动脉狭窄 支架植入术 远期效果 

分 类 号：R743.3[医药卫生—神经病学与精神病学]