上颌骨肿块为首发症状的多发性骨髓瘤1例  

Maxilla mass as the first sign of multiple myeloma: a case report

作　　者：金华萍 单一旦[1] 严奉国[1] 陈关福[1] 

机构地区：[1]浙江大学医学院附属第二医院口腔颌面外科,浙江杭州310000

出　　处：《口腔医学》2017年第12期1115-1119,共5页Stomatology

摘　　要：多发性骨髓瘤是一种浆细胞恶性增殖性疾病,该疾病较好发于男性患者,好发年龄60~70岁。多发性骨髓瘤的首发症状表现形式多样,病灶累及上下颌骨较为常见,但是以颌骨病灶为首发症状较为罕见,本文描述一位55岁女性患者以右侧上颌骨肿块及颏部麻木为首发临床表现,颌骨增强CT及PET/CT检查,结合病理检查,最终诊断为多发性骨髓瘤,提醒口腔医生遇到无法解释的颌骨肿块或感觉异常时,需将多发性颌骨骨髓瘤纳入鉴别诊断,防止误诊或漏诊。Multiple myeloma（MM） is a monoclonal malignant proliferation disease of plasma cells. The disease is more frequently in men and affects individuals aged from 60 to 70 years old. The initial manifestation of MM is various and depends on the sites and extent of involvement. Its occurrence in the maxilla and/or mandible is very common,however oral lesions rarely appear as the first manifestation of the disease. This paper reported a case of a 55 years old female who had a chief complaint of a mass in the right maxilla and the chin numbness. Contrast-enhanced CT and PET/CT scanning showed middle cranial fossa and maxilla and mandible bone diffuse destructive lesions. The biopsy results,imaging and physical examination led to the diagnosis of MM. The findings of the case report suggest that MM should be included in the differential diagnosis and related radiographic and laboratory evaluation should be administered when considering a patient whose complaint is an unusual maxillary and/or mandibular mass.

关 键 词：多发性骨髓瘤 颌骨肿块 颏部麻木 鉴别诊断 

分 类 号：R782[医药卫生—口腔医学] R733.3[医药卫生—临床医学]