血清异常凝血酶原检测在原发性肝癌诊断中的应用价值分析  

Clinical analysis of serum abnormal prothrombin detection in the diagnosis of primary liver cancer

作　　者：黄斌[1] 古善智[1] 黄满平[1] 熊正平[1] 李国文[1] 

机构地区：[1]湖南省肿瘤医院,长沙410013

出　　处：《中国处方药》2018年第1期7-8,共2页Journal of China Prescription Drug

摘　　要：目的探析在原发性肝癌诊断中血清异常凝血酶原检测的应用价值。方法选取2015年12月~2017年6月48例在我院进行检查的原发性肝癌患者为试验组,再选取同一时期48例进行检查的非原发性肝癌患者为对照组,均进行血清异常凝血酶原(PICKAX-Ⅱ)检测以及甲胎蛋白(AFP)检测,观察各组人员的各项指标变化及诊断准确率。结果试验组患者PICKAX-Ⅱ以及AFP指标均明显较对照组高(P<0.05)。此外,PICKAX-Ⅱ对原发性肝癌的诊断准确性及敏感性较AFP高(P<0.05)。结论对于原发性肝癌患者,PICKAX-Ⅱ指标检测的准确性高于AFP,PICKAX-Ⅱ可以作为诊断原发性肝癌的肿瘤标志物,为临床该疾病的诊断提供可靠的理论依据。Objective To investigate the clinical value of serum abnormal prothrombin in the diagnosis of primary liver cancer. Methods From December2015 to June 2017, a total of 48 cases were examined in our hospital in patients with primary liver cancer as the experimental group, and then selected thesame period 48 cases examined non primary liver cancer patients as control group. All patients got abnormal prothrombin（ PICKAX- II） detection and serumalpha fetoprotein（ AFP） detection, then observed the accuracy indicators change and diagnosis of each staff. Results The PICKAX- II and AFP indexes in theexperimental group were significantly higher than those in the control group（ P 〈 0.05）. In addition, the diagnostic accuracy and sensitivity of PICKAX- II toprimary liver cancer was higher than that of AFP（ P 〈 0.05）. Conclusion For patients with primary liver cancer, the application of PICKAX- and AFP weredetected, the index increased significantly. The detection of PICKAX- II index has high accuracy, and AFP can be used as indicators of diagnosis of primaryhepatocellular carcinoma tumor marker, provided theoretical basis for reliable for clinical diagnosis of the disease.

关 键 词：原发性肝癌 血清异常凝血酶原 临床应用 

分 类 号：R735.7[医药卫生—肿瘤]