丁苯酞注射液对急性脑梗死患者神经功能及脂质过氧化的影响分析  

Effect of Butylphthalide Injection on Nerve Function and Lipid Peroxidation in Patients With Acute Cerebral Infarction

作　　者：张建辉[1] 

机构地区：[1]内蒙古通辽市医院神经内一科,内蒙古通辽028000

出　　处：《中国卫生标准管理》2018年第1期79-81,共3页China Health Standard Management

摘　　要：目的研究丁苯酞注射液对急性脑梗死患者神经功能及脂质过氧化的影响。方法将77例急性脑梗死患者分为两组,分别接受基础治疗(对照组38例)及联合丁苯酞注射治疗(观察组39例),对比患者疗效差异。结果观察组患者治疗有效率(74.4%)与对照组患者(57.9%)对比差异存在统计学意义(P<0.05)。观察组患者治疗后NIHSS评分、ox-LDL水平均低于对照组患者(P<0.05)。结论丁苯酞注射液能有效改善急性脑梗死患者神经功能缺损、抑制患者脂质过氧化反应,提升患者治疗效果。Objective To study the effect of butylphthalide injection on nerve function and lipid peroxidation in patients with acute cerebral infarction. Methods 77 patients with acute cerebral infarction were divided into two groups, respectively received basic treatment （control group of 38 cases） and combined with butylphthalide injection treatment （observation group of 39 cases）, the curative effect of patients was compared. Results The effective rate of treatment in the observation group （74.4%） was compared with that of the control group （57.9%）, the difference was statistically signifcant （P 〈 0.05）. The NIHSS score and ox-LDL level in the observation group were lower than those in the control group （P 〈 0.05）. Conclusion Butylphthalide injection can effectively improve the nerve function defect in patients with acute cerebral infarction, inhibit the reaction of lipid peroxidation and improve the therapeutic effect of patients.

关 键 词：丁苯酞注射液 急性脑梗死 神经功能 脂质过氧化 

分 类 号：R743[医药卫生—神经病学与精神病学]