西城区长期住院精神分裂症患者骨质疏松或骨量减少的相关因素研究  

Factors associated with Osteopenia and Osteoporosis in Long-term Hospitalized Schizophrenia in Western Area of Beijing

作　　者：靳玉宏 李小钧[2] 仪玉伟 王志莲 张红芳 王麟 

机构地区：[1]北京市西城区平安医院精神科,北京100035 [2]北京大学国际医院心理科

出　　处：《国际精神病学杂志》2017年第6期975-977,共3页Journal Of International Psychiatry

基　　金：2014年北京市西城区优秀人才培养资助管理项目

摘　　要：目的研究西城区长期住院的精神分裂症患者骨质疏松或者骨量减少的影响因素。方法选取2015年1月~2015年12月在北京市西城区平安医院精神科病房住院精神分裂症患者共148例,分成正常骨密度组(60例)和低骨密度组(88例),主要观察住院患者血钙,血磷,体重指数,催乳素,PANSS,骨密度指标。结果长期住院的精神分裂症患者,低骨密度组与正常骨密度组比较,性别,年龄,催乳素,体重指数,锻炼时间指标均出现明显降低,差异具有统计学意义(P<0.05);且回归模型提示年龄大、催乳素高、体重指数高是骨质疏松的影响因素。结论长期住院的精神分裂症患者中,催乳素高和体型瘦弱的高龄患者,容易出现骨质疏松的情况。Objective The study examined the risk factors for Osteoporosis of patients with chronic schizophrenia.Methods A total of 148 patients with schizophrenia was divided into the normal BMD（60 patients）and decreased BMD（88 patients）,Clinical assessment instruments included Ca,P,body mass index（BMI）,prolactin（PRL）,PANSS,bone mineral density（BMD）.Results The prevalence of osteoporosis was 59.5%（n=148）,The patients in normal BMD compared with those who decreased BMD in sex,age,PRL,BMI,weekly exercises（min）,the difference was significant（P〈0.05）;Multiple logistic regression analysis revealed that age,PRL and BMI were significantly associated with osteoporosis.Conclusion Factors that are associated with Osteoporosis in schizophrenic inpatients are older age,higher BMI,higher PRL level.

关 键 词：精神分裂症 骨质疏松 影响因素 

分 类 号：R749.3[医药卫生—神经病学与精神病学]