积极心理干预对阿尔茨海默病患者药物治疗依从性及精神行为障碍的影响  

Effect of positive psychological intervention on compliance with drug therapy and behavioral and psychogical symptoms of dementia in patients with Alzheimer's disease

作　　者：刘西玲[1] 常巧云[1] 鱼红 苟宁[1] 吉林祝 

机构地区：[1]陕西省人民医院,西安710068

出　　处：《国际精神病学杂志》2017年第6期1091-1094,共4页Journal Of International Psychiatry

基　　金：基金项目 大型公立医院护理岗位管理实施效果研究(编号:2010KRM31);国家临床重点专科

摘　　要：目的探讨积极心理干预对阿尔茨海默病(AD)患者药物治疗依从性及精神行为障碍(BPSD)的影响。方法选择AD患者94例随机分为两组:对照组(n=47)接受常规护理,观察组(n=47)接受积极心理干预8周。评价简易精神状态量表(MMSE)、阿尔茨海默病评估量表(ADAS)和阿尔茨海默病生命质量测评量表(QOL-AD)评分,比较两组药物治疗依从性。结果干预后两组ADAS评分均显著降低,MMSE、QOL-AD评分均显著提高,且观察组改善幅度显著优于对照组(P<0.05);观察组药物治疗依从率为95.74%,显著高于对照组的82.98%(P<0.05)。结论积极心理干预可有效提高AD患者的药物治疗依从性,改善BPSD症状及生活质量。Objective To investigate the effect of positive psychological intervention on compliance with drug therapy and behavioral and psychogical symptoms of dementia（BPSD）in patients with Alzheimer’s Disease（AD）.Methods 94 cases of AD patients were randomly divided into two groups ：The control group（n=47）received routine nursing,and the observation group（n=47）received positive psychological intervention on the basis of control group for 8 weeks.The Mini-Mental State Examination（MMSE）,Alzheimer’s Disease Assessment Scale（ADAS）and Quality of Life-Alzheimer’s Disease（QOL-AD）were evaluated,the compliance with drug therapy were compared between the two groups.Results After invention,he scores of ADAS were significantly decreased,scores of MMSE and QOL-AD were significantly improved in the two groups,the improvements in the observation group were significantly better than the control group（P〈0.05）.The compliance rate of drug therapy in observation group was significantly higher than the control group（95.74% vs 82.98%,P〈0.05）.Conclusion Positive psychological intervention can effectively improve the compliance of drug therapy of AD patients,improve the BPSD symptoms and quality of life.

关 键 词：老年痴呆 精神行为障碍 积极心理干预 依从性 生活质量 

分 类 号：R749.1[医药卫生—神经病学与精神病学]