ATP-MgCl_2联合介入化疗晚期癌疗效观察  

Curative Effect Observation of ATP-MgCl_2 Combined with Interventions Chemotherapy for Advanced Cancer

作　　者：金文昊[1] 金哲洙[1] 李瑞永[1] 李学哲[1] 崔成爱[1] 

机构地区：[1]延边大学医学院附属医院肿瘤科,吉林延边133000

出　　处：《肿瘤防治杂志》2002年第5期518-520,共3页China Journal of Cancer Prevention and Treatment

摘　　要：目的 :探讨ATP MgCl2 加常规抗癌药物局部动脉灌注对晚期恶性肿瘤疗效的影响。方法 :将对象分为A(化疗药 +ATP MgCl2 )和B (单纯化疗药 ) 2组 ,进行动脉灌注治疗 ,并对比 2组临床疗效及其副反应。结果 :A组 4 0例 ,CR 5例 ,PR 8例 ,MR 5例 ,SD 17例 ,PD 5例 ,有效率为 32 5 %。B组 39例 ,CR 1例 ,PR 7例 ,MR 11例 ,SD 14例 ,PD 6例 ,有效率为 2 0 5 %。 2组间未见明显毒副反应差异。结论 :ATP MgCl2 可提高抗癌药物的抗癌作用 ,对一些中、晚期恶性肿瘤具有较好的疗效 ,无明显的毒副反应 ,是一种安全。ObjectiveTo evaluale curative effect of local arterial chemoinfusion with ATP-MgCl 2 and routine anticancer drugs for the advanced cancer.Methods To compare the clinical effect and side effect in group A mes of chemotherapy combined with ATP-MgCl2 and group B of simplex chemotherapy.Results In group A with 40 patients completed response(CR) was 5,patitial response(PR) 8,minor regression(MR)5,stabilized-Disease(SD)17,progressive disease(PD)5,the overall response rate was 32.5%.In group B with 39 patients,CR was 1,PR 7,MR 11,SD14,PD 6,the overall response was 20.5%.There is no significant difference in side effect in two groups.Conlusion ATP-MgCl 2 has obvious anti-cancer function and it has preferable curative effect for some advanced cancer,and no obvious side-effect.It is one kind of safe and effective anti-cancer medicine.

关 键 词：ATP-MGCL2 介入化疗 晚期癌 疗效观察 肿瘤 药物疗法 导管插入术 

分 类 号：R730.53[医药卫生—肿瘤]