缺血性视神经病变患者血浆D-二聚体的水平与预后的相关性  

Correlation between plasma D-two levels and prognosis in patients with ischemic optic neuropathy

作　　者：林再雄[1] 李科[1] 

机构地区：[1]海南医学院附属医院眼科,海口570102

出　　处：《临床眼科杂志》2017年第6期505-507,共3页Journal of Clinical Ophthalmology

基　　金：海南省卫生厅医学科研立项课题(编号:琼卫2012PT-28)

摘　　要：目的研究缺血性视神经病变患者血浆D-二聚体的水平与预后的相关性。方法选择2013年2月至2016年2月于我院诊治的缺血性视神经病变患者180例,所有患者均进行积极治疗,并且测定所有D-二聚体水平数据,另于1个月后以Rankin(mRS)量表展开评分,对比各组患者的预后效果,并且分析预后的效果与D-二聚体水平的相关性。结果根据对比结果和评分结果显示,预后良好的患者(mRS分小于2分)有96例即标识为A组,预后不好的患者(mRS分高于3分)有84例即标识为B组,而在D-二聚体的指标对比方面,A组患者平均为(391.25±29.17)μg/L,而B组患者平均为(372.19±28.21)μg/L。以上数据对比差异显著,符合统计学意义(P<0.05)。结论结合以上预后情况以及D-二聚体的指标对比可知,D-二聚体的增加会直接影响到缺血性视神经病变患者的预后效果,甚至产生隐患问题。Objective To study the correlation between plasma levels of D-two and the prognosis of patients with ischemic optic neuropathy. Methods from February 2013 to February 2016 in our hospital diagnosis and treatment of ischemic optic neuropathy in 180 cases,all patients were active treatment,and the determination of all the D-two polymer level data,Another 1 months after the Rankin（ mRS） scale to expand the score,compared with the prognosis of patients in each group,and analyze the effect of the prognosis and the correlation of D-two polymer level. Results According to the comparison results show that,according to the score display,good prognosis of disease patients（ MRS score less than 2 minutes） with 96 cases that is identified as a group,the prognosis of disease patients（ MRS score higher than 3） 84 cases that is identified as the B group. And in the D-two polymer index contrast,A group of patients with an average of（ 391. 25＋ 29. 17） g/L,and the B group of patients with an average of（ 372. 19 ＋ 28. 21） g/L. The data contrast was significant,and the data was statistically significant（ P〈0. 05）. Conclusions With the combination of the above results and the comparison of D-two indicators,the increase of D-two has a direct impact on the prognosis of patients with ischemic optic neuropathy.

关 键 词：缺血性视神经病变 D-二聚体 预后效果 关联分析 

分 类 号：R774.6[医药卫生—眼科]