中心性渗出性脉络膜视网膜病变的长期随访研究  

Long-term follow-up study of central exudative chorioretinopathy

作　　者：徐朝阳[1] 刘光辉[1] 郑永征[1] 潘铭东[1] 邹国莹 

机构地区：[1]福建中医药大学附属人民医院眼科,福州350004

出　　处：《临床眼科杂志》2017年第6期508-511,共4页Journal of Clinical Ophthalmology

基　　金：福建省中医药科研项目(编号:2017FJZYLC301)

摘　　要：目的观察中心性渗出性脉络膜视网膜病变(CEC)患者长期预后及影响因素。方法对随访5年以上的CEC患者进行回顾性分析,包括患者视力、屈光检查、眼底彩色图像、荧光素眼底血管造影(FFA)及相干光断层扫描(OCT)资料。结果共36例(37只眼)CEC患者,随访时间5~15年,平均9.1年。男性10例(27.8%),女性26例(72.2%)。FFA检查典型性36只眼,隐匿性1只眼。末次随访,最佳矫正视力0.04~1.5,平均0.62±0.28。视力提高者27只眼(73.0%),稳定者9只眼(24.3%),下降者1只眼(2.7%);患者视力预后与初诊视力、黄斑区脉络膜新生血管(CNV)位置、OCT表现IS/OS完整性、治愈时间有关(P<0.05),与治疗方法无关(P>0.05)。结论 CEC患者视力预后较好,其视力预后主要与初诊视力、病变位置、OCT形态、治愈时间相关,治疗干预缩短愈合时间是改善其视力预后的可控性因素。Objective To observe the long-term prognosis and related factors for central exudative chorioretinopathy（ CEC）. Methods Retrospective review was performed in CEC patients with five-year follow-up or longer,and data that were evaluated included best corrected visual acuity（ BCVA）,fundus photos,fundus fluorescein angiography（ FFA）and optical coherence tomography（ OCT）. Results 36 patients（ 37 eyes） with CEC were followed up for 5 ~ 15 years,average 9. 1 years. 10 patients were male（ 27. 8%） and 26 were female（ 72. 2%）. Choroidal neovascularization（ CNV）in 36 eyes were typical based on FFA,and 1 was occult. BCVA ranged from 0. 04 to 1. 5 at the last follow-up,average0. 62 ± 0. 28. BCVA increased in 27 eyes（ 73%）,remained stable in 9 eyes（ 24. 3%）,and decreased in 1 eye（ 2. 7%）. Prognosis of BCVA is related to BCVA of first visit,location of CNV in macula,IS/OS integrity and duration of cure（ P〈0. 05）,regardless treatment method（ P〈0. 05）. Conclusions Prognosis of CEC patients is good. Prognosis of BCVA is mainly related to BCVA of first visit,location of CNV,IS/OS integrity and duration of cure. Duration of cure is controllable factors to improve the BCVA prognosis of CEC patients.

关 键 词：中心性渗出性脉络膜视网膜病变 视觉 预后 

分 类 号：R774.1[医药卫生—眼科]