一类微生物流加发酵过程的动态优化  

Dynamic Optimization for a Class of Microbial Fed-Batch Fermentation Process

作　　者：王丹[1] 李彩霞 徐恭贤[1] 

机构地区：[1]渤海大学数理学院,辽宁锦州121013

出　　处：《重庆理工大学学报（自然科学）》2017年第12期116-121,共6页Journal of Chongqing University of Technology：Natural Science

基　　金：国家自然科学基金资助项目(11101051;11371071);辽宁省自然科学基金资助项目(2015020038)

摘　　要：研究了甘油生物歧化为1,3-丙二醇的流加发酵过程。针对甘油生物歧化为1,3-丙二醇过程的流加发酵系统,建立了在终端时刻是固定值的前提下,以1,3-丙二醇的浓度达到最大值为目标函数的动态优化模型。采用有限元配置法,将甘油流加生物歧化为1,3-丙二醇过程的状态方程转换为代数方程,进而得到模型的NLP(非线性规划)形式。运用Matlab软件求解所建立的动态优化模型,并针对所得到的优化结果进行分析及讨论。The fed-batch fermentation process of glycerol bio-dissimilation to 1,3-propanediol was studied. A dynamic optimization model with the maximum concentration of 1,3-propanediol as the objective function was established under the premise that the terminal time was a fixed value for the fed-batch fermentation system with glycerol bio-dissimilation as 1, 3-propanediol. The NLP（ nonlinear programming） form of the model was obtained by using collocation on finite elements method to convert the state equation of the glycerol bio-dissimilation to the 1,3-propanediol process to the algebraic equation. The dynamic optimization model was solved by Matllab software,and the optimization results were analyzed and discussed.

关 键 词：1 3-丙二醇 动态优化 流加发酵 有限元配置法 

分 类 号：O29[理学—应用数学]