岭南地区痛风危险因素与中医证型相关性分析  

Analysis of the Correlation of Gout Risk Factor and TCM Syndrome in Lingnan Area

作　　者：郭泽莹 张剑勇[1] 张燕英[1] 肖语雅[1] 

机构地区：[1]广州中医药大学第四临床医学院,广东深圳518033

出　　处：《中医药导报》2018年第1期57-59,63,共4页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：痛风性关节炎中医辨证分型规律调查研究(201507051);痛风泰颗粒剂对痛风/高尿酸血症患者血尿酸水平的影响(201402085)

摘　　要：目的:探讨痛风危险因素与中医证型的关系,总结痛风证型分布规律。方法:通过收集痛风患者年龄、病程、BMI指数、证型、合并症等资料,应用统计学方法分析各要素与中医证型的相关性。结果:(1)痛风中医证型分5型,其中湿热蕴结证比例最高(41.9%)。年龄在不同证型的差异无统计学意义(P>0.05),病程、BMI指数在不同证型的差异有统计学意义(P<0.05)。(2)高嘌呤饮食嗜好者(63.9%)、家族史(24.4%)、饮酒史(18.6%)三者在不同证型的差异无统计学意义(P>0.05)。(3)合并高脂血症50例(29.1%),合并高血压24例,高血糖9例。三高在不同证型的分布有明显差异(P<0.01)。结论:湿热蕴结证是岭南地区痛风常见证型:5种证型均离不开湿、热、瘀、虚的病机特点。同一患者随着病程增加,BMI指数改变,均可引起病机的变化,证型随之变化。临床重视痛风合并症有助于判断病机发展及证型规律,在治疗原发病同时也能对其合并症能起到很好的作用。Objective： To explore the correlation of the gout risk factors with TCM syndrome and Conclude gout syndrome regularity. Methods： By collecting gout patients＇ age, course of disease, BMI, syndrome type, complication etc, the relationship of the gout risk factors and TCM syndrome were analyzed using statistical methods. Results： （1）TCM syndrome of gout includs five types, and the most is damp-heat accumulation （41.9%）. Among the five syndromes, age showed no significant differences （P〉0.05）, while course of disease and BMI showed significant differences （P〈0.05）. （2）High purine diet habits （63.9%）, family history （24.4%） and drinking history （18.6%） showed no significant differences among the syndromes （P〉0.05）. （3） There were 50 cases combined hyperlipidemia （29.1%）, 24 cases combined hypertension, and 9 cases combined hyperglycemia. These three complications showed significant differences among the syndromes （P〈0.01）. Conclusion： Damp-heat accumulation was the most common syndrome in Lingnan area. The five syndromes were inseparable from the pathogenesis characteristics of dampness, heat, blood stasis and deficiency. Syndromes could change when the course of disease or BMI changed. To attach importance to gout complications could help determine pathogenesis and syndrome type, and cure the complication while curing the primary disease.

关 键 词：痛风 危险因素 证型 相关性 

分 类 号：R22[医药卫生—中医基础理论]