酶法合成单脂肪酸甘油酯的反应体系研究进展  

Research progress on the reaction system of fatty acid monoglycerides by enzymatic synthesis

作　　者：王瑞 张桂菊 邓成龙 王肖彦 徐宝财 

机构地区：[1]北京工商大学食品学院,北京市食品风味化学重点实验室,北京市食品添加剂工程技术研究中心,北京100048 [2]北京理工大学化学与化工学院,北京100081

出　　处：《食品与发酵工业》2017年第12期224-231,共8页Food and Fermentation Industries

基　　金：国家自然科学基金项目(21676003);国家重点研发计划项目(2017YFB0308701);北京市教委科技计划重点项目(KZ201510011010);北京市教委市属高校创新能力提升计划项目(TJSHG201510011020)

摘　　要：由于反应条件温和、选择性高、安全环保,酶法合成单脂肪酸甘油酯近年来受到了科学家们的广泛关注。单脂肪酸甘油酯的酶法合成工艺关键在于反应过程中酶活性的保持以及反应底物的混溶性,即酶催化反应体系的选择与调控。文中重点介绍了常见的酶催化反应体系在酶法合成单脂肪酸甘油酯中的应用研究进展,主要包括有机溶剂体系、反胶束体系、无溶剂体系、超临界流体体系和离子液体体系等。最后,对酶法合成单脂肪酸甘油酯的反应体系作了总结和展望。Lipase-catalyzed synthesis of fatty acid monoglycerides has obtained a lot of research interests in recent years due to its mild reaction conditions,high selectivity,safety and greens environmental protection. The key to the enzymatic synthesis of fatty acid monoglycerides is the maintenance of enzyme activity and the miscibility of the reaction substrates during the reaction,that is,the selection and regulation of the enzymatic reaction system. The research progress on several enzymatic reaction systems of enzymatic synthesis of fatty acid monoglycerides is mainly introduced herein,such as organic solvent system,reverse micellar system,solvent-free system,supercritical fluid system and ionic liquid system. Finally,the advantages and disadvantages of aforementioned enzymatic reaction systems were summarized and forecasted.

关 键 词：单脂肪酸甘油酯 酶法合成 反应体系 

分 类 号：TQ641[化学工程—精细化工]